Forty-nine biopsies of bulbar conjunctiva from patients with no apparent conjunctival disease were studied by light and transmission electron microscopy. No significant morphological changes were recorded in those specimens from patients less than 79 years old. However, in the older age group the epithelium showed irregularities in thickness, a reduction in the goblet cell population, and in 25...

BACKGROUND Hyaline body myopathy (HBM) is a rare chronic nonprogressive congenital myopathy, with variable patterns of inheritance. METHODS We describe a patient with congenital HBM with progression of weakness and increasing muscle pain in adulthood. Three muscle biopsies, done at various times in her life, are reported. RESULTS Symptoms started during childhood; however, as an adult, foll...