نتایج جستجو برای: malt lymphomas
تعداد نتایج: 19284 فیلتر نتایج به سال:
t(11;18)(q21;q21) is a specific chromosomal translocation associated with mucosa-associated lymphoid tissue (MALT) lymphoma. It fuses the amino terminal of the API2 gene to the carboxyl terminal of the MALT1 gene and generates a chimeric fusion product. Although the translocation is frequently detected in gastric and pulmonary MALT lymphoma, its incidence in MALT lymphomas from other sites is l...
In most H. pylori-positive patients, gastric low-grade mucosa-associated lymphoid tissue (MALT) lymphomas regress both endoscopically and histopathologically after H. pylori eradication, but no factors that can be predictive of the response to the eradication have been definitively identified, and there is little information on how to determine the optimal observation period before additional t...
BACKGROUND Hepatitis C virus (HCV) infection is frequently associated with B-cell non-Hodgkin's lymphomas. We investigated the prevalence of HCV infection in nongastric marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT) in order to define the relationship between the viral infection and the presenting features, treatment, and outcome. METHODS We retrospectively studied 172 pa...
BACKGROUND/AIMS Helicobacter pylori eradication therapy has been used as a first-line treatment for H. pylori-positive gastric mucosa-associated lymphoid tissue (MALT) lymphoma. However, the management strategy for H. pylori-negative MALT lymphoma remains controversial. Therefore, the aim of this study was to examine the success rate of each treatment option for H. pylori-positive and H. pylori...
The development of gastric mucosa-associated lymphoid tissue (MALT) lymphoma is a multistep process and can be clinico-pathologically divided into Helicobacter pylori-associated gastritis, low-grade tumors, and high-grade tumors. The molecular events underlying this progression are largely unknown. However, identification of the genes involved in MALT lymphoma-specific t(11;18)(q21;q21) and t(1...
Non-Hodgkin lymphoma usually arises from lymphoid or nodal tissue, and can occasionally involve other sites. Extra-nodal marginal-zone B-cell lymphoma of mucosaassociated lymphoid tissue (MALT lymphoma) is uncommon and constitutes around 8% of all non-Hodgkin lymphomas. Most MALT lymphomas are of gastric origin and lung involvement is rare. Primary pulmonary lymphoma is defined as clonal lympho...
Most colonic multiple mucosa-associated lymphoid tissue (MALT) lymphomas are confirmed with a histologic and immunohistochemical staining of the mucosal biopsy specimen obtained during colonoscopic examinations. Endoscopically, colonic MALT lymphomas frequently appear as protruding and/or ulcerative lesions, and there are not so many reports of colonic MALT lymphoma as compared to the frequent ...
Extranodal marginal zone B-cell lymphoma is a discrete clinicopathological entity arising in mucosa-associated lymphoid tissue (MALT) that has commanded increasing attention in recent years because of its unique pathogenetic, histologic, and clinical features.1-3 Two types of MALT can be identified in disparate organs that do not correspond to peripheral sites of the immune system. The native t...
Aberrant DNA hypermethylation is an important mechanism for the inactivation of tumor-related genes in human tumors. Gastric mucosa-associated lymphoid tissue (MALT) lymphomas arise from Helicobacter pylori-associated chronic gastritis; most patients are H. pylori-positive and eradication therapy is highly effective. In the present study, we used methylation-specific PCR to analyze the DNA meth...
Anatomically, mucosa-associated lymphoid tissue (MALT) is found in various parts of the body. In the colon, lymphoid tissue occurs mainly as isolated lymphoid follicles that are composed mainly of B lymphocytes. Such gastrointestinal tract MALT plays an important role in immune surveillance and mucosal regeneration, but the cells inMALTmayoccasionally undergo abnormal proliferation and give ris...
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