This minireview discusses the use of mass spectrometry in biomarker discovery, the current utility of these markers for bacterial identification after culture, and the potential for nonculture-based diagnosis of infectious diseases. The bases of these thoughts are the independent revolutions that have occurred in the fields of molecular biology and analytical chemistry, leading to the current i...

In this study, the hyphenation of gas chromatography with ICP tandem mass spectrometry (GC-ICP-MS/MS) for analysis volatile organochlorides in complex hydrocarbon samples is described.

This work presents the validation study of comprehensive two-dimensional gas chromatography-time of flight mass spectrometry (GC×GC-TOFMS) method performance in analysis of the key WADA anabolic agents in doping control. The relative abundance ratio, retention time, identification and other method performance criteria have been tested in the GC×GC format to confirm if they comply with those set...

A human serum sample collected from a victim of the Osaka VX incident was analyzed according to our developed technique for metabolites of VX. Gas chromatography-mass spectrometry (GC-MS) in full-scan electron impact and chemical ionization modes were used, and, for more reliable confirmation, GC-MS-MS was also employed. In the serum sample, both ethyl methylphosphonic acid and 2-(diisopropylam...

In this study, star anise (Illicium verum) essential oils (SAEOs) were extracted by hydrodistillation (HD), ethanol solvent extraction (ESE), supercritical CO2 (SCD) and subcritical (SE) via electronic nose (E-nose), gas chromatography-mass spectrometry (GC-MS), GC-ion mobility (GC-IMS). GC-MS GC-IMS used to identify the volatile compounds, was also determine their concentrations. Principal com...

Background: Analysis of pesticide residues in food and other environmental commodities have become an essential requirement for consumers, producers, food inspectors and authorities. This study is focused on validation of an accurate, rapid and reliable method for multi-residual analysis of pesticides in pistachio as a strategic crop for export and one of the main nuts in Iranian food basket.Me...

The review describes on-line derivatization/degradation methods employed in mass spectrometry to solve some structural and analytical problems. Advantages and applications of various positions of reaction systems connected mainly to a mass spectrometer or a gas chromatograph/mass spectrometer are considered. Among these are reaction systems connected directly to the mass spectrometer (reaction ...

Gas chromatography/mass spectrometry (GC/MS) of the MOD flake Micro-samples (3.3 mg from the MOD flake and less than 1 mg from the other samples, see below) were collected from the specimens and submitted to an analytical procedure (GC/MS) in order to identify lipids, waxes, proteins, resinous materials and saccharides [1-2]. GC/MS had already been successfully employed for the characterization...

A method for characterization of airborne particles including the nanoparticles fraction with a diameter of 29-58 nm in roadside atmosphere has been described. The method consists of thermal extraction (TE) and comprehensive two-dimensional gas chromatography (GC x GC) with novel detection capabilities, including high resolution time-of-flight mass spectrometry (HRTOF-MS), and simultaneous sele...

Mass spectrometry has long been used in clinical laboratories. The first important applications were the use of gas chromatography–mass spectrometry (GC-MS) for drug screening and the diagnosis of organic acid metabolic disorders. More recently liquid chromatography–mass spectrometry [LC-MS; liquid chromatography–tandem mass spectrometry (LC-MS/MS)] has been introduced successfully into clinica...