A fast and low-cost analytical method to determine the concentrations of carotenoids (β-carotene, lutein, lycopene) from mixed standard solutions or fruit extracts (kiwi fruits, tomato paste, pink grapefruit juice, kiwi-pineapple smoothie, apricot nectar) was tested. The methodology based on UV-Vis spectrophotometry Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS). Results show...

For the first time, we report a series of time resolved images of a single PLGA microparticle undergoing hydrolysis at 70 C that have been obtained using attenuated total reflectance-Fourier transform infrared spectroscopic (ATR-FTIR) imaging. A novel partially supervised non-linear curve fitting (NLCF) tool was developed to identify and fit peaks to the infrared spectrum obtained from each pix...

For the first time, we report a series of time resolved images of a single PLGA microparticle undergoing hydrolysis at 70 °C that have been obtained using attenuated total reflectance-Fourier transform infrared spectroscopic (ATR-FTIR) imaging. A novel partially supervised non-linear curve fitting (NLCF) tool was developed to identify and fit peaks to the infrared spectrum obtained from each pi...

• MCR-ALS with EFA is applied in the analysis of lipid bilayers FT-IR spectra. Phase transition temperatures are obtained from various signatures lipids. All give equal values main phase temperatures. Different parts display slightly different pretransition Possibility for separation events related suggested. Temperature-dependent transmission spectroscopy and DSC measurements were conducted on...

A new methodology is proposed to describe the evolution of main chemical compounds grape must during wine alcoholic fermentation using Attenuated Total Reflectance Mid Infrared (ATR-MIR) spectra in combination with Multivariate Curve Resolution Alternating Least-Squares (MCR-ALS). In addition, we have developed a process control strategy detect differences between fermentations running under No...

Abstract. A powerful methodology, based on the multivariate curve resolution alternating least squares (MCR-ALS) method with quadrilinearity constraints, is proposed to handle complex and incomplete four-way atmospheric data sets, providing concise results that are easy interpret. Changes in air quality by nitrogen dioxide (NO2), ozone (O3), particulate matter (PM10) eight sampling stations loc...

There is an increasing need to use multivariate statistical methods for understanding biological functions, identifying the mechanisms of diseases, and exploring biomarkers. In addition to classical analyses such as hierarchical cluster analysis, principal component analysis, and partial least squares discriminant analysis, various multivariate strategies, including independent component analys...