Thlyroxine, important in the metamorplhosis of amphibians, as well as in the (lifferentiation of mammalian tissues, exerts its effects on suclh diverse tissues as cartilage, liver and brain(l). Effects of thyroxinie at the celltular level have been variously ascribed to its uncoupling of oxidlative phosphorylation(2), its direct interaction with enzymes(3,4), and its stimulation of mitochondria...

M-DNA (mitochondrial deoxyribonucleic acid) from a variety of animals ranging from insects to mammals, prepared for electron microscopy by the protein monolayer technique (15), has been shown to be in the form of a circle (3, 4, 13, 16, 18-22, 24). The contour lengths of the circles of any one species have a Gaussian distribution with a small standard error. The M-DNA's of many vertebrates appe...

Distributed along the coastal waters of Korea and China, Octopus minor is found in various habitats, including the mud flats in the southern and western coasts of the Korean Peninsula and the rocky areas around Jeju Island; however, the genetic relationships among the different populations are unknown and have not been studied. We compared 630-nucleotide sequences of the CO1 gene fro...

Parkinson’s disease (PD) is an adult-onset disease of unknown etiology, with a prevalence of 0.3% in the entire population, affecting more than 1% of humans over 60 years of age. Primary degeneration occurs in pigmented dopamine-containing neurons in the pars compacta of the substantia nigra, with projections to the striatum and typical motor signs that appear with a loss of 60% of the dopamine...

In this review, the potential causes of ageing are discussed. We seek to gain insight into the main physiological functions of mitochondria and discuss alterations in their function and the genome, which are supposed to be the central mechanisms in senescence. We conclude by presenting the potential modulating role of the kynurenine pathway in the ageing processes. Mitochondrial dynamics are su...