a 64-year-old woman, with amyloid related kidney failure (on renal dialysis) had a bone scan because of pain in the right upper femur. the 99m tc-mdp images revealed marked hepatic uptake. in addition, there was right proximal femoral concentration of radiotracer, which corresponded to a fracture site. as an added finding, the same femor demonstrated circumferential uptake at the lower pole. th...

Purpose: To assess the role of 18F-NaF PET/CT in detection metastatic bone disease compared to 99mTc-MDP scan (+/-SPECT/CT). Methods: 64 adult patients with locally advanced primary tumor were enrolled this study. All underwent pretherapy and scan. Results: Among revealed positive metastases 26 patients, only 19 them have results scan, while remaining 7 falsely negative On other hand diagnosed ...

Background: Melorheostosis has been discussed infrequently in the nuclear medicine literature. A 25-year-old female patient presented with a one-year history of b:union: pain, sclerotic change and skin pigmentation on the left big toe interphalangeal joint. Ulceration, poor healing and hyperkeratoses of the wound were noted post debridement. The plain film of the left foot incidentally showed m...

Introduction: The purpose of the present study was to evaluate the effect of prednisolone on the sensitivity of bone scanning to detect the simulated closed fracture in the rat tibia.  Methods: A total number of forty eight adult, male NMRI rats randomly assigned into two parts, one part for 4 and other for 8 weeks experiments. Each part has been divided into four groups, one group not receivi...

F-18 NaF PET/CT has been shown to have higher sensitivity than planar 99m-Tc MDP bone scanning in several studies. The concomitant acquisition of anatomic images permits immediate correlation of any abnormal findings. Additionally, F-18 NaF PET/CT bone imaging can be quantitated, allowing bone disease to be 'measureable', increasing its utility therapy monitoring. When a consistent F-18 NaF upt...

Osteo-cutaneous flap are commonly used for reconstruction of bone defect after oncology surgery. The success of surgery depends on the viability of the bone flap. Bone scan is a known, but less performed method, to look for viability of bone flaps. We describe a case of 50-year-old lady, presenting with squamous cell carcinoma of left buccal mucosa (cT4N1M0) involving the skin and mandible. She...

Received 1/4/2005; revised 1/8/2005; accepted 1/18/2005. For correspondence or reprints contact: Bing-Fu Shih, M.D., Department of Nuclear Medicine, Mackay Memorial Hospital, 92 Section 2, Chung-Shan North Road, Taipei 104, Taiwan. Tel:(886)2-25433535 ext. 2241, Fax: (886)2-25433535 ext. 2925, E-mail:[email protected] Bone scintigraphy is a common and sensitive modality for detecting either...

Bone scans are widely utilized for detection of metastases from bone sarcomas. Technetium methylene diphosphonate scan ([(99m)Tc]MDP) is one of the most popular radiotracers used for that purpose. Lymphatic spread of bone sarcomas is unusual and often difficult to diagnose. Unfortunately, bone scans are not as sensitive in demonstrating lymphatic spread of sarcomas as they are at demonstrating ...

This study analyzed 99Tcm-MDP bone scans and investigated factors influencing early-stage castration resistance in prostate cancer (CRPC) patients with bone metastasis. We retrospectively analyzed clinical data from 92 patients with bone metastatic prostate cancer treated with maximal androgen blockade. Patients were imaged with 99Tcm-MDP bone scan to detect metastases, and prostate specific an...