A causal link between decreases in white matter (WM) integrity and cortical degeneration is assumed, but there is scarce knowledge on the relationship between these changes across the adult human lifespan. We investigated changes in thickness throughout the cortical mantle and WM tract integrity derived from T1 and diffusion weighted magnetic resonance imaging (MRI) scans in 201 healthy adults ...

Surrogates of whole-brain white matter (WM) networks reconstructed using diffusion tensor imaging (DTI) are novel markers of structural brain connectivity. Global connectivity of networks has been found impaired in clinical Alzheimer's disease (AD) compared to cognitively healthy aging. We hypothesized that network alterations are detectable already in preclinical AD and investigated major glob...

In contrast to middle age, it is unclear whether blood pressure (BP) in older persons is associated with cerebral small vessel disease (cSVD). The authors evaluated the association of BP with signs of cSVD as well as gray and white matter integrity in older persons. In 220 participants aged 75 years and older from the Discontinuation of Antihypertensive Treatment in the Elderly (DANTE) study, c...

Integrity checking is a crucial issue, as databases change their instance all the time and therefore need to be checked continuously and rapidly. Decades of research have produced a plethora of methods for checking integrity constraints of a database in an incremental manner. However, not much has been said about when to check integrity. In this paper, we study the differences and similarities ...

if we think of the graph as modeling a network, the vulnerability measure the resistance of the network to disruption of operation after the failure of certain stations or communication links. many graph theoretical parameters have been used to describe the vulnerability of communication networks, including connectivity, integrity, toughness, binding number and tenacity.in this paper we discuss...

Through real-life experiments, it has been proved that spoofing is a practical threat to applications using the free civil service provided by Global Navigation Satellite Systems (GNSS). In this paper, we demonstrate a prototype that can verify the integrity of GNSS civil signals. By integrity we intuitively mean that civil signals originate from a GNSS satellite without having been artificiall...

Introduction: Our aim was to compare the nuclear DNA integrity of the spermatozoa from infertile men with abnormal semen parameters with that from normospermic fertile men, and to evaluate the relationship between the sperm DNA integrity and semen parameters. Materials and Methods: Thirty ejaculate samples with abnormal semen analysis and 30 ejaculates with normal semen parameters were randomly...

Twin studies have indicated a common genetic origin for intelligence and for variations in brain morphology. Our previous diffusion tensor imaging studies found an association between intelligence and white matter integrity of specific brain regions or tracts. However, specific genetic determinants of the white matter integrity of these brain regions and tracts are still unclear. In this study,...

a special class of cubic graphs are the cycle permutation graphs. a cycle permutation graph pn(α) is defined by taking two vertex-disjoint cycles on n vertices and adding a matching between the vertices of the two cycles.in this paper we determine a good upper bound for tenacity of cycle permutation graphs.

oxidative stress has been identified as a crucial factor leading to male infertility largely due to peroxidativedamage to the sperm cell membrane. cadmium (cd) is a widespread environmental pollutant and oneof the well-known reproductive toxicants. because of its long biological half-life (10–30 years), cdaccumulates in the biological systems. the present study was designed to assess the concen...