Measurement of the carotid intima-media thickness enables arterial wall thickening to be quantified during preclinical disease stages. However, little is known about how the thickness varies in individuals with no cardiovascular risk factors. The objective of this study was to report on the range of carotid intima-media thicknesses observed in a population of healthy subjects with no cardiovasc...

objective(s): atherosclerosis is an important risk factor for coronary heart disease. neuropeptide y (npy) and its receptors, located in peripheral tissue such as white adipose tissue, have been linked to obesity and fat storage. the role of npy in atherosclerosis has not yet been fully studied, so this study was conducted to further investigate the effect of biie 0246, an npy receptor antagoni...

OBJECTIVE To describe and test a practical protocol to measure common carotid intima-media thickness that uses the combined values of two longitudinal examination angles to increase sensitivity. METHOD Between February and September 2005, 206 patients underwent duplex scan examination of carotid vessels, and the intima-media thickness of 407 common carotids were measured in three angles: tran...

While hypertension is known to cause left ventricular and vascular hypertrophy, the relationship between alterations of vascular and cardiac structures in patients with hypertrophic cardiomyopathy has not been fully clarified. We measured intima-media thickness of carotid arteries by ultrasonography in patients with hypertrophic cardiomyopathy (n = 16), normotensive subjects (n = 358), and hype...

INTRODUCTION AND OBJECTIVES Carotid intima-media thickness as measured with ultrasonography is an inexpensive and noninvasive predictor of cardiovascular events. The objectives of this study were to determine the population reference ranges of carotid intima-media thickness for individuals aged 35-84 years in Spain and to analyze the association of carotid intima-media thickness with cardiovasc...

BACKGROUND Ultrasonographic assessments of intima-media thickness and plaques in the carotid artery are widely used as surrogate markers for coronary atherosclerosis, but prospective evaluations are scarce and appear to be lacking in patients with coronary artery disease. Ultrasonographic evaluations of femoral vascular changes have not been studied prospectively. METHODS AND RESULTS In the A...

The aim of this study is to evaluate the carotid artery intima media thickness and serum lipids in pediatric patients with epilepsy treated with valproic acid. The study included 44 pediatric epileptic and 40 healthy children. Intima media thickness of left common carotid artery and fasting lipid profile (total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipopr...

INTRODUCTION The measurement of carotid artery intima-media thickness in children and adolescents has attracted a great deal of research and clinical interest in recent years, because it can provide evidence that early arterial lesions are already present in asymptomatic subjects who have risk factors for cardiovascular disease. The aim of the present study was to investigate possible correlati...