alzheimer’s disease (ad) is a uniquely human disorder. although the pathogenesis of ad is not fully understood, growing evidence indicates that the deposition of beta-amyloid (aβ) and the local reactions of various cell types to this protein play major roles in the development of the disease. in the present study transgenic mice expressing mutant amyloid precursor protein (app) has been used. t...

the aim of this review article is to analyze the clinical effectiveness of total knee replacement (tkr) compared to unicompartmental knee replacement (ukr) in patients with medial unicompartmental osteoarthritis (muo) in terms of survival rates, revision rates and postoperative complications. the search engine was medline. the keywords used were: medial knee osteoarthritis. three thousand and n...

Recent research in cognitive neuroscience has supported the idea that active rehearsal of information over short delays, or working memory maintenance, is accomplished by activating long-term memory representations. Nonetheless, it is widely assumed that although the human hippocampus and related medial temporal lobe structures may be critical for the formation of long-term memories, they are n...

Purpose: Genu varum deformity changes the line of gravity from center of knee towards the medial side. This deviation results in changes in the upper part of the lower extremity that can affect postural control as well as the position and activity of the proximal muscles of the knee joint, like the gluteus medius muscle. Therefore this study aims to investigate the effect of genu varum disorder...

Talar compression fractures are uncommon orthopaedic injuries, especially in the immature skeleton. Fractures of the talar body constitute >5% of all foot and ankle fractures. The combination of a medial compression fracture and corresponding medial malleolar fracture is rare and not previously reported injury in the literature. We present a case report of a skeletally immature 15-year-old Cauc...

purpose: to present an extraocular muscle disinsertion in a pterygium surgery case report: a 61-year-old woman presenting an acute diplophia after a nasal pterygium surgery. the medical rectus muscle was cut during the primary surgery which was immediately reported and the muscle was reinserted to its original site and recovery was more or less obtained. conclusion: anatomical consideration met...

This article presents a case of insufficiency fracture of medial proximal tibia caused by long-term administration of saccharated ferric oxide (SFO) in a 77-year-old female. In this case, 2-year administration of SFO for iron deficit anemia induced hypophosphatemic osteomalacia and finally resulted in an insufficiency fracture of medial proximal tibia. Hypophosphatemia and pain due to the insuf...