melasma is a common acquired skin disorder. while different treatments are currently being used, in many cases it is refractory to treatment. according to the effects of topical steroids in decreasing skin pigmentation, we studied the efficacy of this new method for treatment of melasma. a total of 42 women with facial melasma, admitted to the department of dermatology of hamadan, were enrolled...

Melasma is a localized, chronic acquired hypermelanosis of the skin. Despite several treatments available, melasma can often be refractory to treatment. Also recurrences are common. Tranexamic acid is a new addition in treatment of melasma and is effective in dosage of 250 mg BD for atleast 4 to 8 weeks. Tranexamic acid acts mainly via the plasminogen activator-plasmin system to prevent UV radi...

introduction: ablative and nonablative lasers have been used to treat melasma. we aimed to assess and compare the combining q-switched nd:yag laser (qsnyl) and fractional erbium:yag laser (feyl) with qsnyl alone in treatment of melasma. methods: this randomized controlled clinical trial was performed in our research center during 2013-2014. women with melasma and without a history of keloid for...

BACKGROUND Recently, low fluence collimated Q-switched (QS) Nd:YAG laser has drawn attention for the treatment of melasma. However, it needs a lot of treatment sessions for the substantial results and repetitive laser exposures may end up with unwanted depigmentation. OBJECTIVE We evaluated the clinical effects and safety of the combinational treatment, using intense pulsed light (IPL) and lo...

Melasma is a common hypermelanotic disorder affecting the facial area which has a considerable psychological impact on the patient. Managing melasma is a difficult challenge that requires long-term treatment with a number of topical agents, such as rucinol and sophora-alpha. Aims. We aim to compare the combined treatment of skin needling and depigmenting serum with that using depigmenting serum...

most contemporary clinical reasoning tests typically assess non-automatic thinking. therefore, a test is needed to measure automatic reasoning or pattern recognition, which has been largely neglected in clinical reasoning tests. the puzzle test (pt) is dedicated to assess automatic clinical reasoning in routine situations. this test has been introduced first in 2009 by monajemi et al in the oly...

Introduction: Melasma is main cause of facial hyperchromia and has a significant psychosocial impact. Wood’s lamp been useful device to estimate the depth melanin determined by light-induced fluorescence. A dermoscope enables clear visualization pigments distribution, color variation will depend on its location within skin. Methods: cross-sectional observational study was conducted at outpatien...

INTRODUCTION Few studies have focused on therapeutic as well as side effects of tranexamic acid (TXA) as a topical drug compared to other topical drugs in treating melasma. The present study aimed to assess and compare the beneficial therapeutic effects and also side effects of local TXA in comparison with hydroquinone in treating women with melasma. METHODS This randomized double-blinded cli...

ABSTRACT Background: Melasma, a common dermatological problem which has no standard recommended therapy. This study aimed to compare the clinical efficacy of combined trichloroacetic acid peel and ascorbic with alone in epidermal melasma. Methods: A quasi-experimental was conducted on 148 patients melasma, dermatology department Pak Emirates Military Hospital, Rawalpindi from August 2019 Januar...