The quality of analgesia, patient satisfaction and incidence of side effects following a single bolus of epidural morphine were compared with patient-controlled epidural analgesia (PCEA) with meperidine during the first 24 hr after elective Caesarean section. Seventy-five women were randomly assigned to three equal groups. Group I received 30 mg epidural meperidine after delivery and PCEA with ...

OBJECTIVE To compare the efficacy and safety of intramuscular meperidine injection with periprostatic nerve block (PNB) during transrectal ultrasound-guided prostate biopsy. METHODS This study was carried out from July 2010 to June 2012 at the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China. This controlled, double-blinded, randomized study included 186 patients....

BACKGROUND A common and useful approach to pain management is administration of neuraxial opioids. OBJECTIVES Whether addition of fentanyl or meperidine to lidocaine and epinephrine for spinal anesthesia in elective cesarean delivery has any effects on duration of postoperative pain. PATIENTS AND METHODS This was a clinical trial, conducted on 195 pregnant women candidates for elective cesa...

background pain following laparoscopy could be due to different causes requiring effective postoperative analgesia. objectives in the present study, we evaluated the combined effect of intraperitoneal infiltration of bupivacaine-meperidine versus intravenous infusion of paracetamol on pain relief after diagnostic gynecologic laparoscopy. conclusions intraperitoneal infiltration of bupivacaine w...

BACKGROUND Shivering is a frequent event during the perioperative period. We performed a prospective, randomized, double-blind study to determine whether intrathecal meperidine (0.2 mg/kg) decreases the incidence and intensity of shivering after spinal anesthesia for transurethral operations. METHODS Fifty patients scheduled for elective transurethral resection operations under spinal anesthe...

BACKGROUND Arthroscopic knee surgeries have a painful postoperative course, which often necessitates acute pain management. Among different analgesia techniques, Intra-articular injection is the technique of choice for many pain specialists, based on its confined effect to the surgical site (knee), lack of systemic effects and promotion of safe early ambulation. OBJECTIVES The aim of this stu...

Meperidine (Demerol(®)) is a mu- and kappa-opiate receptor agonist used for moderate to severe pain. Overdose can result in respiratory depression, hypotension and coma, while accumulation of its toxic metabolite, normeperidine, can cause delirium and seizures. Little data exist examining the inter- and intrasubject variability of the normeperidine-to-meperidine metabolic ratio (MR) in urine. T...

BACKGROUND Concern has been expressed that epidural analgesia for labour may be associated with a higher incidence of backache. METHODS A prospective randomized trial investigating the effect of epidural analgesia on the outcome of labour in nulliparae, mothers were randomized to receive either epidural analgesia or meperidine. A questionnaire on postnatal symptoms was sent to them 6 months a...

BACKGROUND Shivering is a frequent event during spinal anesthesia and meperidine is a well-known effective drug for prevention and treatment of shivering. Nefopam is a non-opiate analgesic and also known to have an anti-shivering effect. We compared nefopam with meperidine for efficacy of prevention of shivering during spinal anesthesia. METHODS Sixty five patients, American Society of Anesth...

conclusions intravenous acetaminophen reduced pain following outpatient urological surgery more significantly than meperidine. patients and methods in a prospective, randomized, double-blind clinical trial, 100 outpatients of urological surgery were studied in two groups of acetaminophen (a) and meperidine (m). patients in group a received 1g of acetaminophen in 100 ml saline within 15 minutes ...