Conventional allogeneic bone marrow transplantation after myeloablation can prevent experimental autoimmunity and has been proposed as treatment for humans. However, trace populations of donor hematolymphoid cells persisting in solid organ allograft recipients have been associated in some circumstances with therapeutic effects similar to replacement of the entire bone marrow. We therefore exami...

Mercury is a widespread environmental and industrial pollutant, which induces severe effects on human animal bio-systems. The experiment was designed to investigate the of different concentrations mercuric chloride (Hgcl2) hemato-biochemical histological changes liver kidney in female Swiss Albino mice. A total 24 numbers mice 28-30 days’ age were randomly assigned into 4 equal groups (n=6) as ...

Mercury exposure is a common cause of metal poisoning which is biotransformed to highly toxic metabolites thus eliciting biochemical alterations and oxidative stress. Luteolin, a phenolic compound found in many natural products, has multiple biological functions. Our study was aimed to explore the biological effects of luteolin in a liver injury model induced in rats by mercuric chloride (HgCl2...

Mercurials may induce immune manifestations in susceptible individuals. Mercuric chloride (HgCl2) induces autoimmunity in the Brown Norway (BN) strain but an immunosuppression in the Lewis strain with, however, autoreactive anti-class II T cells present in both strains. In the present study we looked at modifications of cytokine production by PCR and cytofluorometric analyses in normal BN and L...

The effects of mercuric chloride (HgCl2), indole-3-acetic acid (IAA) and their combination on the development of different cell types in the stem of Lagenaria siceraria (Mol) Standl. were studied. Mercury treatment resulted in a reduced stem diameter when compared to untreated control plants. This is attributed to a decrease in the diameter of fibre cells, sieve tube members, large xylem vessel...

Many studies have reported on the toxicity and related oxidative stress of mercury. Antioxidants play an important role in counteracting metal-induced neurotoxicity under in vivo conditions. In this study, the effect of diallylsulphide (DAS) was evaluated on mercuric chloride induced activities of catalase, superoxide dismutase, glutathione peroxidase and glutathione content in brains of rats. ...

The study was aimed to evaluate the possible effects of dexamethasone on oxidant/antioxidant status in kidney tissues of rats administered mercuric chloride (HgCl2). Thirty male Wistar-albino rats were enrolled in this study. Rats were divided into 4 groups: G1 (n=7) underwent no therapy (control group), G2 (n=8) received HgCl2 + physiological saline, G3 (n=7) dexamethasone (DM) + physiological...

A Chesapeake Bay water isolate of Mycobacterium scrofulaceum containing a 115-megadalton plasmid (pVT1) grew in the presence of 100 microM HgCl2 and converted soluble 203Hg2+ to volatile mercury at a rate of 50 pmol/10(8) cells per min. Cell extracts contained a soluble mercuric reductase whose activity was not dependent on exogenously supplied thiol compounds. The enzyme displayed nearly ident...