Introduction Maintaining oxygen homeostasis is of vital importance for the survival and development of mammalian cells. Hypoxia (below-normal levels of oxygen in air, blood and tissue) can potentially lead to cellular dysfunction and ultimately cell death and is a feature of many pathological conditions. Understanding how reduced oxygen levels may contribute to or even promote disease is a sign...

Compared to most of the traffic modeling techniques used today, TES (Transform-Expand-Sample) is among the youngest ones. Its basic scheme consists of creating a randomly governed background sequence, smoothing it and finally adapting it to a given marginal distribution, altogether yielding a foreground sequence. In this scheme, the so-called Stitching Function originally is responsible for rem...

Most executives know the basics of negotiation; some are spectacularly adept. Yet even experienced negotiators routinely leave money on the table, end up in deadlock, damage relationships, or allow conflicts to spiral. They fall prey to common mistakes that keep them from solving the right negotiation problem. In any negotiation, each side ultimately chooses between two options: accepting a dea...

for an Invited Paper for the MAR10 Meeting of The American Physical Society DNA: Not Merely the Secret of Life NADRIAN C. SEEMAN, New York University DNA is well-known as the genetic material of living organisms. Its most prominent feature is that it contains information that enables it to replicate itself. This information is contained in the well-known Watson-Crick base pairing interactions, ...