The MET pathway plays a key role in various cancers, and its inhibition represents a potential treatment target. However, appropriate biomarkers are needed to facilitate the selection of patients who would benefit from MET inhibiting therapy. We herein conducted a robust confirmatory evaluation of the MET copy number alteration status and prognostic significance of c-Met expression in a large s...

Background: This retrospective study compared pregnancy outcomes from single embryo transfer (SET) with multiple embryo transfer (MET) in too young (≤25 years) and young (>25 years) infertile patients. Materials and Methods: Data from infertile patients who referred for ART treatment to Yazd infertility center during 1992 to 2012 were studied retrospectively. Records of patients with SET or MET...

Introduction: Methomyl (MET) is a carbamate insecticide, used in agriculture and public health to eliminate harmful insects. Besides its advantages in agriculture, it causes neurotoxic effects. The aim of this study was to evaluate the effect of MET on Spatial Working Memory (SWM), oxidative stress parameters,  and histopathological changes in the hippocampus, as well as the possible protective...

background: methionine has been suggested as the firstlimitingamino acid for milk production in ruminants. it is importanthow to increase milk protein yield and milk fat in dairy ruminants.objectives: this study was set to investigate the effect of rumenprotected methionine (rpmet) on milk composition of lactatingcashmere rayeni goats. methods: 40 healthy singletoncashmere rayeni goats about 3 ...

In this paper we present results from analysis of GPS/MET occultation data obtained from the University Corporation for Atmospheric Research database. We have used High-Rate occultation data to study the performance of an earlier 4D ionospheric electron content model|obtained tomographically with the use of the GPS constellation|with satisfactory results. In addition, we have processed UCAR Lev...

Our aim was to investigate both the prevalence of MET amplification in gastric cancer as well as the potential of this genetic alteration to serve as a therapeutic target in gastric cancer. MET amplification was assessed by initial screening with a PCR-based copy number assay followed by confirmatory FISH analysis in formalin-fixed, paraffin-embedded specimens of gastric cancer obtained at surg...

OBJECTIVE To examine the expression of c-Met, c-Erb-b2 (HER2/neu), and epidermal growth factor (EGFR) in a cohort of 12 chordomas, based on the current and future availability of targeted molecular inhibitors. DESIGN Protein expression levels were analyzed by immunohistochemical analysis from archival tissue using multitumored tissue microarray and by Spearman rank correlation test. SETTING...