The prevalence of metabolic disorders, such as type 2 diabetes (T2D), obesity, and non-alcoholic fatty liver disease (NAFLD), which are common risk factors for cardiovascular disease (CVD), has dramatically increased worldwide over the last decades. Although dietary habit is the main etiologic factor, there is an imperfect correlation between dietary habits and the development of metabolic dise...

Background: Metabolic syndrome (MS) and non-alcoholic fatty liver disease (NAFLD) is a common public health problem. Visfatin is secreted by visceral adipose tissue and is an adipocytokine. It could be a pro-inflammatory adipocytokine and is related to the metabolic syndrome and non-alcoholic fatty liver disease. This study evaluated the association between visfatin levels in patients w...

BACKGROUND Liver transplantation for inherited metabolic disorders aims to save the patient's life when the disorder is expected to progress to organ failure, and to cure the underlying metabolic defect. METHODS We retrospectively analyzed 146 pediatric liver transplants (28 metabolic; 118 non-metabolic) performed between 1986 and 2000. RESULTS Twenty-eight transplants were performed in 24 ...

Reactive oxygen species (ROS) play a significant role in the survival and decline of various biological systems. In liver-related metabolic disorders such as steatohepatitis, ROS can act both cause consequence. Alcoholic steatohepatitis (ASH) non-alcoholic (NASH) are two distinct types steatohepatitis. Recently, there has been growing interest using medications that target formation reduce leve...

Background Metabolic-associated fatty liver disease (MAFLD) is a newly proposed definition and there limited data on MAFLD prevalence. We aimed to investigate the prevalence of in an eastern Chinese population. Methods This cross-sectional study included participants from population who underwent regular health checkups. Based current diagnostic criteria, was diagnosed individuals with both hep...

background: recent studies demonstrated that resveratrol has many therapeutic effects on liver disorders. resveratrol significantly increased survival after liver transplantation, decreased fat deposition, necrosis, and apoptosis which induced by ischemia in wistar rats. it provided liver protection against chemical, cholestatic, and alcohol injury. resveratrol can improve glucose metabolism an...

background: the aim of this study was to assess the association between insulin resistance, metabolic syndrome and nonalcoholic fatty liver disease (nafld) in chinese adults. methods: fifty five subjects with nafld and 55 controls were enrolled for the study. waist circumference, blood pressure, plasma triglyceride, high density lipoprotein cholesterol and fasting plasma glucose concentrations ...

INTRODUCTION Hepatocellular carcinoma (HCC) is a major cause of cancer worldwide. The vast majority of cases occur in individuals with a chronic HBV or HCV infection. In addition, a number of metabolic diseases of the liver are associated with the development of HCC. PATHOPHYSIOLOGIC MECHANISMS The mechanisms responsible for the progression of the metabolic liver disease and HCC differ from t...

post-transplant lymphoproliferative disorder is a lymphocyte proliferating disease, usually of b cell origin, and rarely of t cell. involvement of liver itself in liver transplant recipients as the primary organ is not common. herein we report our experience in two patients who primarily presented in the allografted liver, both of whom were promptly diagnosed after liver biopsy and treated succ...

conclusions: prevalence of fatty liver is high in our obese children. it was associated with criteria of metabolic syndrome and insulin resistance, so visceral fat may participate in the pathogenesis of the metabolic syndrome or merely serve as a marker of increased risk for the metabolic complications of obesity. patients and methods: 102 obese iranian children, referred to pediatric clinics f...