the lipid accumulation product is a novel, safe and inexpensive index of central lipid over accumulation based on waist circumference and fasting concentration of circulating triglycerides. this study was designed to investigate the ability of lipid accumulation product to predict cardio-metabolic risk factors in postmenopausal women. in this cross-sectional study, 264 postmenopausal women by u...

The presence of the metabolic syndrome, a clustering of metabolic risk factors closely associated with abdominal obesity, is accompanied by an increased risk for the development of cardiovascular diseases and type 2 diabetes mellitus. It is now generally accepted that insulin resistance together with abdominal obesity are key features in the pathophysiology of the metabolic syndrome. As a resul...

BACKGROUND We aimed to explore the agreement among World Health Organization (WHO), European Group for the Study of Insulin Resistance (EGIR), National Cholesterol Education Program (NCEP), American College of Endocrinology (ACE), and International Diabetes Federation (IDF) definitions of the metabolic syndrome. METHODS 1568 subjects (532 men, 1036 women, mean age 45 and standard deviation (S...

OBJECTIVE In recent years, several major organizations have endorsed the concept of the metabolic syndrome and developed working definitions for it. How well these definitions predict the risk for adverse events in people with the metabolic syndrome is only now being learned. The purpose of this study was to summarize the estimates of relative risk for all-cause mortality, cardiovascular diseas...

OBJECTIVE The optimum definition of the metabolic syndrome (MS) is not known. We compared international definitions of MS [recently proposed modified definition of National Cholesterol Education Programme, Adult Treatment Panel III (NCEP, ATP III) and International Diabetes Federation (IDF)] with two proposed candidate definitions in adult Asian Indians. DESIGN Data from three previous cross-...

Metabolic Syndrome and Early Death To the Editor: The editorial by Franks and Olsson1 highlights the heterogeneous nature of definitions of the metabolic syndrome, which results from the number of different combinations of risk factors that equate with a diagnosis of the syndrome. However, the situation is even more complex than indicated in Figure 2 of their editorial. There are, in fact, 16 p...

OBJECTIVE The aim was to evaluate the impact of specific component combinations of the metabolic syndrome on all-cause mortality risk in a large French cohort. RESEARCH DESIGN AND METHODS The population was composed of 39,998 men (aged 52.6 +/- 8.3 years) and 20,756 women (aged 54.7 +/- 9.2 years) who were examined at the Investigations Préventives et Cliniques Center from 1999 to 2002. Mean ...

BACKGROUND AND PURPOSE The purpose of this study was to compare definitions of metabolic syndrome with regard to their prediction of stroke and coronary heart disease incidence. METHODS The study comprises 4041 men and 3812 women of 6 Finnish and Swedish cohorts aged 25 to 74 years at baseline. Hazard ratio was estimated applying Cox regression analyses adjusting for cohort, cholesterol, and ...

BACKGROUND The prevalence of the metabolic syndrome among a number of Asian populations as defined by several current criteria has been increasing rapidly and appears to resemble that among Western populations. METHODS We review 25 surveys of the metabolic syndrome in Asian populations (PR China, Hong Kong, Taiwan, Japan, Philippines, Singapore) that report adequate information published duri...