sentinel lymph node is the first regional lymph node that drains the lymph from the primary tumor. it is potentially the first nodeto receive the seeding of lymph‑borne metastatic cells. this study aimed to discuss lymphoscintigraphy procedural guidelines fordetection of sentinel node using tc‑phytate in isfahan, iran. moreover, the preliminary results of the first year’s clinical experience of...

Axillary lymph node status is the most important prognostic factor in predicting disease outcome in women with breast cancer. A number of chromosomal aberrations in primary breast tumors have been correlated with lymph node status and clinical outcome, but chromosomal changes particular to metastatic lymph node tumors have not been well studied. DNA samples isolated from laser-microdissected pr...

Sentinel lymph node (SLN) status is the most accurate predictor of survival in melanoma patients with clinically negative regional nodes [1,2]. Until recently, metastatic S...

BACKGROUND Lymph node metastasis is a key event in the progression of breast cancer. Therefore it is important to understand the underlying mechanisms which facilitate regional lymph node metastatic progression. METHODOLOGY/PRINCIPAL FINDINGS We performed gene expression profiling of purified tumor cells from human breast tumor and lymph node metastasis. By microarray network analysis, we fou...

Lymph node status is a key prognostic factor in penile squamous cell carcinoma. Recently, growing evidence indicates a multimodality approach consisting of neoadjuvant chemotherapy followed by consolidation surgery improves the outcome of locally advanced penile cancer. Thus, accurate estimation of survival probability in node-positive penile cancer is critical for treatment decision making, co...

BACKGROUND Recurrent laryngeal nerve (RLN) lymph node metastasis used to be shown a predictor for poor prognosis in esophageal squamous cell carcinoma. The purpose of this study was to evaluate the prognostic impact of RLN node metastasis and the number of metastatic lymph nodes in node-positive patients with squamous cell carcinoma of middle thoracic esophagus. METHODS A cohort of 235 patien...

background: sentinel  lymph  node  biopsy  has  shown  to  be  a  good  alternative procedure  for  axillary  lymph  node  dissection  and  to lead  to  lower  frequency  of morbidity, though this technique has its own side effects. it needs especial equipment and may not be available in some medical centers, especially in developing countries. this study aimed to identify a subgroup of patient...

BACKGROUND AND OBJECTIVE Intraoral squamous cell carcinoma (OSCC) is one of the common tobacco related cancers affecting Indian population. These tumours are slow growing, endophytic and are mostly well differentiated. Cervical lymph node is the common site of metastasis of these tumours. In most of the patients cervical lymph node metastasis rather than the primary tumour, affects prognosis. H...

clinically apparent cervical lymphadenopathy has been found at the initial presentation in 23 to 56 % of cases of papillary thyroid carcinoma. here we report tuberculous lymphadenitis mimicking metastatic lymph nodes from papillary thyroid carcinoma and suggest that tuberculosis apart from metastasis in papillary thyroid carcinoma should also be considered in the etiology of enlarged lymph node...