Various treatments have been considered as the cornerstone for management of patients with metastatic renal cell carcinoma (mRCC) over past two decades. Currently, immunotherapy is a promising clue in landscape frontline treatment mRCC. Immune checkpoint inhibitors (ICIs), which constitute standard therapy pretreated mRCC patients, are emerging … Continued

UNLABELLED Metastatic renal cell carcinoma in the gallbladder is extremely rare, with reported frequencies of less than 0.6% in large autopsy reviews. Only 40 cases were reported in the literature. We report a first case of gallbladder polypoid tumor revealing metastatic clear cell renal cell carcinoma, which demonstrates the importance of radiological tests, histology and immunohistochemistry ...

1. Toyoda Y, Shinohara N, Harabayashi T. Survival and prognostic classification of patients with metastatic renal cell carcinoma of bone. Eur Urol. 2007;52:163–9. 2. Sheth S, Scatarige JC, Horton KM. Current concepts in the diagnosis and management of renal cell carcinoma: role of multidetector CT and three-dimensional CT. Radiographics. 2001;21:237–41. 3. Zisman A, Pantuck AJ, Dorey F. Improve...

Management of bone metastases from Renal Cell Carcinoma (RCC) has significantly changed after the era targeted therapy that improved overall survival. This sucked different interveners in their management to push surgical indications order improve outcome and quality life for these patients. In case a solitary metastasis or limited number resectable wide resections have be considered according ...

Renal cell carcinoma (RCC) accounts for only 3% of adult malignancies, and the lung is the most common site of metastasis of this tumor, which may be accompanied by pleural metastasis. However, solitary pleural involvement is very rare and its presentation with dyspnea as the first manifestation of RCC is extremely rare.We describe a 39-year-old male with episodes of dyspnea dating back 6...

Metastatic tumors of the oral cavity are rare in occurrence. Renal cell carcinoma (RCC) metastasizes to organs head and neck 12–16% cases. RCC metastases tongue uncommon. A total 63 cases kidney cancer metastasizing have been reported literature. We report a clinical case metastasis skin lower eyelid (as initial manifestation disease) (11 months after diagnosis) one patient with metastatic canc...

objective(s): the ability to measure cellular proliferation non-invasively in renal cell carcinoma may allow prediction of tumour aggressiveness and response to therapy. the aim of this study was to evaluate the uptake of 18ffluorothymidine (flt) pet in renal cell carcinoma (rcc), and to compare this to 18f-fluorodeoxyglucose (fdg), and to an immunohistochemical measure of cellular proliferatio...

A 52-year-old woman had a pathological fracture of the right femur. On histopathological examination bone metastasis from renal cell carcinoma was suspected. Abdominal computed tomography showed a heterogeneous mass (9.1 x 7.8 x 6.5 cm) in the left kidney and a cystic multilocular mass (12 x 10 cm) in the pelvis. Bone scintigraphy revealed an abnormal uptake in the left coracoid process, right ...

Transmembrane protein 174 (TMEM174) mRNA is easily detectable in human kidney tissues and activates AP-1 and promotes 293T cell proliferation. In the present study, RNA in situ hybridization was used to detect TMEM174 gene expression in various malignant renal cancer and normal renal tissues. The results showed that TMEM174 exhibits differential expression in renal tissues, with a high positive...