The concentration of Cr in several tissues in response to high-level, short-term supplementation was used to determine the relative bioavailability among 4 organic Cr sources and to assess the relative safety of high levels of supplementation. Crossbred pigs (n = 40; mean BW = 48.1 +/- 0.9 kg) were allotted to 5 diets: a control diet with no added Cr, or 5,000 microg/kg of Cr from Cr tripicolin...

Calorie restriction (CR) remains the most robust intervention to extend lifespan and improve health span. Using a global mass spectrometry-based metabolomic approach, we identified 193 metabolites that were significantly differentially expressed (SDE) in the livers of C57BL/6 mice, fed graded levels of CR (10, 20, 30 and 40% CR) compared to mice fed ad libitum for 12 h a day. The differential e...

It has been reported that the C0-C4 carbons of methionine are converted to ethylene in FMN-light (23) and Cu"!-ascorbate (10) model systems. Yang (22) has shown that C-C, carbons of 2-keto-4-methylthiobutyrate and the Cr, carbons of 3-methylthiopropionaldehyde (i.e., methional) are converted to ethylene in a model peroxidase system. When methionine was fed to apple tissue, the C-C4 carbons were...

Multidose protein formulations require an effective antimicrobial preservative (AP) to inhibit microbial growth during long-term storage of unused formulations. m-cresol (CR) is one such AP, but it has been shown to cause protein aggregation. However, the fundamental physical mechanisms underlying such AP-induced protein aggregation are not understood. In this study, we used a model protein cyt...

in order to determination the methionine requirement of arian broilers chickens during the starter period, a trial with 700 broiler chickens in a completely randomized design with 7 treatments, 5 replicates and 20 chicks in each experimental units was performed. experimental groups were consisted of 0.38, 0.43, 0.48, 0.53, 0.58, 0.63 and 0.68  % of methionine. other amino acids provided higher ...

A 12-wks laying trial was conducted to study the effect of dietary chromiummethionine chelate supplementation on laying Japanese quail (Coturnix coturnix japonica) performance, egg quality, fertility %, hatchability % and some plasma constituents during summer months. A total of 225 laying Japanese quail (150 ♀+ 75 ♂) of 8 wks old were randomly assigned in 5 equal groups of 3 equal replicates e...

The importance of homoserine in the metabolism of amino acids in a variety of living forms is now well established. This amino acid was found to be the common precursor of methionine and threonine in Neurospora crassa (1). Enzymes involved in the conversion of aspartic acid to threonine via homoserine have been studied in Escherichia coli (2-5) and in bakers’ yeast (6-S). The presence of homose...

Metabolic demands of early lactation introduce enormous challenges to dairy cows when coincided with environmental stresses. The objective of this study was to determine effects of a chromium (Cr) supplement on feed intake and blood indicators of nutrient metabolism in early lactation cows in summer. Fifteen Holstein cows at 38±6 days in milk were grouped based on parity and randomly assigned t...

Description Creatine is a naturally occurring amin (~1 g/day-1 [~0.04 oz.]) occurs in the glycine, arginine, and methionine. Cr daily requirement of ~2 to 3 g [~0.1 o Approximately 3 to 5 g [~0.1 to 0.2 o uncooked meat or fish. Dietary creat enters the bloodstream. Most (95 pe muscle. Sixty to seventy percent of s phosphocreatine (PCr), which is effe the anaerobic production of adenosin g [~4 o...

Creatine (Cr) has been shown to increase the total muscle mass. The purpose of this study was to investigate the effect of Cr supplementation on muscle morphology and swimming performance, using an animal model. Each rat was subjected to exercise 15-minute period daily for the 12 weeks. The rats were randomly divided into four groups: no Cr supplementation (CON), no Cr supplementation and incom...