To evaluate the impact of gender and ablation β-carotene oxygenase 1 (BCO1), 2(BCO2) or both on tissue accumulation lycopene dosed transgenic mice. Previous work from our laboratories suggests that BCO2 appears to be primary carotenoid cleavage enzyme for in vivo. Three-week old C57BL/6 male female mice (wild type [WT], Bco1-/-, Bco2-/-, Bco1-/- X Bco2-/- double knock out [DKO]) were divided in...

Metronidazole is used to treat trichomoniasis, bacterial vaginosis, and other diseases. There are controversy aspects about its teratogenicity. A teratogenic agent can alter morphology or subsequent function of the fetus. The aim of this study was to examine an alternative method for the recognition of the mechanism or the bimolecular potential changes in mice fetus caused by Metronidazole usin...

objectives: toxoplasma gondii is a coccidian protozoon which forms tissue cyst in different organs of infected intermediate host. the present study was conducted to demonstrate the active form of parasite in different tissues of rat, which was experimentally infected with rh strain of toxoplasma gondii using bioassay method inmice. materials & methods: in the experimental assay, 75 rats an...

With the prevalence of obesity and obesity-related metabolic syndrome, such as insulin resistance in recent years, it is urgent to explore effective interventions prevent progression syndrome. Palmitoleic acid a monounsaturated fatty that available from dietary sources, mainly derived marine products. plays positive role maintaining glucose homeostasis reducing inflammation. However, still unkn...

Phenobarbital is a phenobarbiturate used as a sedative, anticonvulsant or hypnotic with the doses prescribed and can cause teratogenic effects. The goal of this study was to examine an alternative method for the recognition of the mechanism or the bimolecular potential changes in mice fetus caused by Phenobarbital using FTIR micro spectroscopy. The mice were injected with Phenobarbital (120 mg/...

Abstract In this study, D-galactose was used to establish a model of liver dysfunction caused by oxidative stress in mice, and the effect dandelion on improving exercise capacity mice with observed its mechanism expounded. This study examined role running ability, swimming endurance, blood biochemical indices, histopathological changes, tissue mRNA expression changes. The animal results showed ...

Background: Trace elements play an important role in a number of biological processes. Astaxanthin (ASX), a carotoid pigment found in certain marine plant and animals, has shown anti cancer and anti free radical properties. This work intended to understand the effect of Astaxanthin in breast cancer (invasive ductal carcinoma, IDC) by using micro-pixe method. For this aim the concentratio...