OBJECTIVE To investigate cell biological changes in calcified aortas of rats that experienced chronic renal failure. METHODS AND RESULTS Vascular smooth muscle cells have the potential to transdifferentiate to either chondrocytes or osteoblasts, depending on the molecular pathways that are stimulated. Uremia-related medial calcification was induced by feeding rats an adenine low-protein diet ...

BACKGROUND Thyroid nodules are a common clinical problem that require close attention to determine the risk of malignancy. This study was designed to investigate the diagnostic values of pathological characteristics, ultrasonographically-detected calcification, and serum TSH levels in thyroid cancer in Han Chinese. METHODS A retrospective analysis was carried out using 1,685 patients with thy...

Microcomputerized tomography (micro-CT) allows discriminating very smal lchanges in dental hard tissue volumes. The aim of the present study was to create a new method for obtaining high-resolution, three-dimensional images of dental hard tissue development using micro-CT, and to observe the changes in dental hard tissue development and composition in growing rat pups. Tooth germs from rats at ...

In this paper we present a boosting based approach for automatic detection of micro-calcifications in mammographic images. Our proposal is based on using local features extracted from a bank of filters for obtaining a description of the different micro-calcifications morphology. The approach performs an initial training step in order to automatically learn and select the most salient features, ...

Nowadays breast cancer is one of the major causes of death among women. This shows an early diagnostic techniques is critical for women’s quality of life. Mammography is the main test used for screening and early diagnosis of breast cancer. Since micro calcifications are space-occupying lesions, described by their shapes, margins etc several image processing based techniques have been developed...

Coral reefs, and the unique ecosystems they support, are facing severe threats by human activities and climate change. Our understanding of these threats is hampered by the lack of robust approaches for studying the micro-scale interactions between corals and their environment. Here we present an experimental platform, coral-on-a-chip, combining micropropagation and microfluidics to allow direc...