نتایج جستجو برای: microbiota interaction

تعداد نتایج: 595907  

Journal: :Inflammation & allergy drug targets 2014
Enayat Nikoopour Bhagirath Singh

Adaptation of the whole microbial normal flora residing in a host to its natural habitat over an evolutionary peroid has resulted in peaceful coexistence with mutual benefits for both microbiota and host in steady state. This symbiotic relationship between host and microbiota has a significant impact on shaping the immune response in the host to achieve an immune tolerance to microbiota but ret...

Journal: :Biomedical journal 2015
Dali Ma Gilles Storelli Mélanie Mitchell François Leulier

The complex interaction between the metazoan host and its commensal gut microbiota is one of the essential features of symbiosis in the animal kingdom. As there is a burgeoning interest to decipher the molecular dialog that shapes host-microbiota mutualism, the use of gnotobiotic model organism becomes an imperative approach to unambiguously parse the specific contributions to such interaction ...

Journal: :Computation 2015
Scott Christley Chase Cockrell Gary An

A large and growing body of research implicates aberrant immune response and compositional shifts of the intestinal microbiota in the pathogenesis of many intestinal disorders. The molecular and physical interaction between the host and the microbiota, known as the host-microbiota interactome, is one of the key drivers in the pathophysiology of many of these disorders. This host-microbiota inte...

2015
Ru Feng Jia-Wen Shou Zhen-Xiong Zhao Chi-Yu He Chao Ma Min Huang Jie Fu Xiang-Shan Tan Xiao-Yang Li Bao-Ying Wen Xi Chen Xin-Yi Yang Gang Ren Yuan Lin Yangchao Chen Xue-Fu You Yan Wang Jian-Dong Jiang

The gut microbiota is important in the pathogenesis of energy-metabolism related diseases. We focused on the interaction between intestinal bacteria and orally administered chemical drugs. Oral administration of berberine (BBR) effectively treats patients with metabolic disorders. However, because BBR exhibits poor solubility, its absorption mechanism remains unknown. Here, we show that the gut...

2015
Rahul Shubhra Mandal Sudipto Saha Santasabuj Das

Gut microbiota of higher vertebrates is host-specific. The number and diversity of the organisms residing within the gut ecosystem are defined by physiological and environmental factors, such as host genotype, habitat, and diet. Recently, culture-independent sequencing techniques have added a new dimension to the study of gut microbiota and the challenge to analyze the large volume of sequencin...

2018
Chloe Heys Anne Lizé Hervé Colinet Thomas A. R. Price Mark Prescott Fiona Ingleby Zenobia Lewis

The microbiota is increasingly being recognized as having important impacts on many host biological processes. However, evidence of its effects on animal communication and breeding strategy is lacking. In this three-factorial study, we show that females were more willing to mate with related males, with relatedness likely being assessed through the microbiota. By contrast, male mating investmen...

Journal: :Annals of parasitology 2012
Marcin M Grzybowski Henryka Długońska

Numerous original and review papers have emerged over recent years concerning the natural microbiota and its interaction with the mammal host's body. This addendum supplements in short our previous review article on the role of microbiota in the host immunity paying, particular attention to such essential aspects as the composition and role of gut microbiota in viral infections as well as the i...

2018
Qingqing Feng Wei-Dong Chen Yan-Dong Wang

The gut microbiota, as the main member in gut microecology, is an essential mediator in health and disease. The gut microbiota interacts with various organs and systems in the body, including brain, lung, liver, bone, cardiovascular system, and others. Microbiota-derived metabolites such as the short chain fatty acid (SCFA) butyrate are primary signals, which link the gut microbiota and physiol...

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