The paper studies the compressibility of directly compressible tableting materials with dry binders, spray-dried lactose and microcrystalline cellulose, and glyceryl dibehenate at various concentrations. Compressibility was evaluated by means of the energy profile of compression and tensile strength of tablets. Release rate of the active ingredient, salicylic acid, from the tablets was also exa...

Degradation of cotton cellulose by Trichoderma reesei endoglucanase I (EGI) and cellobiohydrolase II (CBHII) was investigated by analyzing the insoluble cellulose fragments remaining after enzymatic hydrolysis. Changes in the molecular-size distribution of cellulose after attack by EGI, alone and in combination with CBHII, were determined by size exclusion chromatography of the tricarbanilate d...

A novel greener method to impregnate silver nanoparticles (AgNPs) into microcrystalline cellulose (MCC) by curry leaf (Murraya koenigii) extract is presented. The active reduction of silver ions by curry leaf extract was explored for the in situ impregnation AgNPs into MCC. Transmission electron microscopy (TEM) analysis of MCC coated with AgNPs showed the formation of silver particle sizes in ...

This work demonstrates the preparation of spherical nanocellulose from microcrystalline cellulose by controlled hydrolysis using anaerobic microbial consortium. The nanocellulose formed during the degradation of microcrystalline cellulose was separated by ultra filtration membrane and purified by differential centrifugation. The purified nanocellulose was characterized by nanoparticle size anal...

The crystalline structure of cellulose has been studied for a long time. It is well known that crystallinity of cellulose can be measured using quite a number of methods, X-ray diffraction, solid state C CP-MAS NMR, Fourier transforminfrared (FT-IR) spectroscopy and Raman spectroscopy. The solid state C CP-MAS NMR and FT-IR spectroscopy considers contributions from both crystalline and non-crys...

Microcrystalline cellulose I (MCCI) is an excipient used as a diluent, disintegrant, glidant and binder for the production of pharmaceutical tablets. In this work, microcrystalline cellulose II (MCCII) was obtained from cotton fibers by basic treatment with 7.5 N NaOH followed by an acid hydrolysis. MCCI and MCCII materials were processed by wet granulation, dry granulation and spray drying. Ei...

The effects of magnesium stearate, sodium lauryl sulphate (SLS) and talc as lubricants on some powder and tablet properties of silicified microcrystalline cellulose (SMCC) were studied. Single and binary blends of talc, magnesium stearate and SLS at 1% concentration were evaluated as flow modulators on SMCC. Influence of the lubricants on the powder and tablet properties of metronidazole was al...

A cDNA expression library of the rumen fungus Neocallimastix patriciarum was made in Escherichia coli. Cellulolytic clones were identified by screening on a medium containing carboxymethylcellulose. Restriction mapping and Southern hybridization analysis of selected clones revealed three distinct cellulase cDNAs, designated celA, celB and celC. Studies on the substrate specificity showed that t...

Introduction: The results presented here are part of an investigation into the evolution of hydrothermal events associated with the Chicxulub impactites in Yu-catan, Mexico. The study focuses on alteration products in core samples recovered from the Yaxcopoil-1 drill hole, which is located some 60 kilometers from the center of the impact structure. This research contributes to the growing knowl...