نتایج جستجو برای: microdose gnrh
تعداد نتایج: 7008 فیلتر نتایج به سال:
0
This white paper summarizes a study comparing MicroDose Diagnostic Scan to geometric magnification for imaging fine image details, and explains the efficiency of the Diagnostic Scan functionality of the MicroDose system based on two phantom studies. Highlights of these studies reveal: • Diagnostic Scan, an exclusive feature of Philips MicroDose Mammography, helps discern fine details in spot co...
The microdosing strategy allows for early assessment of human pharmacokinetics of new chemical entities using more limited safety assessment requirements than those requisite for a conventional phase I program. The current choice for evaluating microdosing is accelerator mass spectrometry (AMS) due to its ultrasensitivity for detecting radiotracers. However, the AMS technique is still expensive...
PURPOSE To demonstrate the safety and surgical feasibility of the first-in-man ocular implant of a novel Posterior MicroPump Drug Delivery System (PMP) in patients with diabetic macular edema (DME) and to report on the device capabilities for delivering a programmable microdose. METHODS This was a single center, single arm, open-label, prospective study. Eleven patients with DME and visual ac...
Determining the pharmacokinetics (PKs) of drug candidates is essential for understanding their biological fate. The ability to obtain human PK information early in the drug development process can help determine if future development is warranted. Microdosing was developed to assess human PKs, at ultra-low doses, early in the drug development process. Microdosing has also been used in animals t...
The technique of accelerator mass spectrometry (AMS) was validated successfully and used to study the pharmacokinetics and disposition in dogs of a preclinical drug candidate (7-deaza-2'-C-methyl-adenosine; Compound A), after oral and intravenous administration. The primary objective of this study was to examine whether Compound A displayed linear kinetics across subpharmacological (microdose) ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید