Pursuing a higher response signal is the core challenge in improving detection performance of microelectrode-based amperometric electrochemical sensor. Band microelectrode arrays (bMEAs) are attractive due to their high current and economical fabrication process. However, further amplifying by arranging array more compactly or increasing its size generally hindered shielding effect restricted c...

A linear array of eight individual addressable microelectrodes has been developed in order to perform high-throughput scanning electrochemical microscopy (SECM) imaging of large sample areas in contact regime. Similar to previous reports, the soft microelectrode array was fabricated by ablating microchannels on a polyethylene terephthalate (PET) film and filling them with carbon ink. Improvemen...

We report a new fabrication technique for realizing a high-density penetrating metal microelectrode array intended for acute multipleunit neural recordings. The microelectrode array consists of multiple metal (Permalloy, Ni80Fe20) shanks projecting from a silicon supporting bulk. Neuron recording sites are located at the tip of each shank. The average distance between recording sites is 50 μm. ...

We developed the fibrin gel-based C2C12 myotube culture system integrated with the microelectrode array device to afford a physiologically relevant and stable bioassay system. Myotube/fibrin gel culture system was prepared by transferring a myotube monolayer from a glass substrate to a fibrin gel while retaining the original line patterns of myotubes. By attaching the myotube/fibrin gel onto th...

In article number 2000223, Silvia Ronchi, Michele Fiscella, and co-workers show neurons plated on a high-density microelectrode array. The small electrode size the tight spacing between 26 400 electrodes enable functional extracellular electrophysiological characterization of across scales, from subcellular-resolution features, like axons dendrites, through individual neuronal cells to entire n...

We have developed a hydrogel-based microstamp device that internally contains an electrochemical system for controlled supply of reactive ink to the stamp surface. An agarose stamp was combined with a microelectrode system for the controlled supply of HBrO by an electrochemical reaction. The supplied HBrO will detach the heparin layer pre-coated on substrates and allow selective adsorption of p...