Dry film photoresist is used for creating microfluidic structures by sandwiching the patterned resist in between of two substrates. The technique is applied for creating hybrid biochips for dielectrophoretic cell manipulation. Multiple level lithography is demonstrated and biocompatibility of the resist is proven. Due to simple fabrication procedures the resist can be processed in a low-tech en...

Biochips, a novel technology in the field of biomolecular analysis, offer promising alternative to conventional testing equipment. These chips integrate multiple functions within single system, providing compact and efficient solution for various needs. For biochips, pattern-control micro-electrode-dot-array (MEDA) is new, universally viable design that can replace microchannels other micro-com...

In this work, a new MEMS technology for hot embossing using polydimethylsiloxane (PDMS) tools is developed and characterized. The developed technology will permit low cost, simple, and rapid fabrication of disposable microfluidic biochips and plastic microstructures for numerous BioMEMS applications. For traditional planar systems, a negative photoepoxy (SU-8) or thick positive photoresist (AZ4...

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Microfluidic biochips revolutionize biology by placing laboratory functionality on a very small chip. The subject of this thesis is a flow-based biochip, which consists of thin channels in which fluids flow. The basic building block of the chip is a valve, which can direct the flow by blocking or unblocking channels. The valves are combined to create components like switches, mixers, and mul-ti...

Digital microfluidic biochips (DMFB) are rectangular arrays of electrodes, or cells, that enable precise manipulation of nanoliter-sized droplets of biological fluids and chemical reagents. Due to the safety-critical nature of their applications, biochips must be tested frequently, both off-line (e.g., post-manufacturing) and concurrent with assay execution. Under both scenarios, testing is acc...

-We propose a novel microfluidic system for continues particles separation by using capillary force and evaporating force. Typically, the microfluidic system needs external force or extra pumps to drive fluids, which were caused system complexity. It is a kind of the simple method to utilize evaporation force and capillary force on driving liquid. The particles can be continuously separated acc...