OBJECTIVES To investigate whether the micronutrients that were shown to reduce the risk of development of age-related macular degeneration in the Age-Related Eye Disease Study (AREDS) can have the same effect on the development of diabetic retinopathy in rats, and to understand the possible mechanisms. METHODS Streptozotocin-induced diabetic rats received a powdered diet with or without suppl...

in order to study the effects of different levels of cow and chicken manure and elemental sulfur (s) on availability of plant nutrients and their uptake by corn (zea mays l.), a factorial experiment was conducted using a completely randomized design and three replication. experimental treatments were three levels (0, 10 and 20 ton ha-1) of cow and chicken manures, and three levels (0, 0.25% and...

It is known that deficiencies of micronutrients due to infections increase morbidity and mortality. This phenomenon depicts itself conspicuously in developing countries. Deficiencies of iron, vitamins A, E, C, B12, etc are widely prevalent among populations living in the third world countries. Helicobacter pylori (H pylori) infection has a high prevalence throughout the world. Deficiencies of s...

Diets very rich in cereals have been associated with micronutrient malnutrition, and the biofortification of them, has been proposed as one of the best approaches to alleviate the problem. Durum wheat is one of the main sources of calories and protein in many developing countries. In this study, 46 durum varieties grown under full and reduced irrigation, were analyzed for micronutrients and phy...

The oral cancer is one of the most prevalent type of cancer worldwide. It is invariably linked to lifestyle habits like alcohol consumption, cigarette smoking and poor nutritional status. This apart, the role of micronutrients in oral carcinogenesis still remains less understood. So the study was undertaken to assess the micronutrient levels of oral cancer and precancerous patients.The estimati...

Heart failure is a multifactorial disease with poor prognosis. There are many hypotheses regarding the cause of heart failure. Leading among them are the hemodynamic and the neuro-hormonal hypotheses. Although the energy depletion hypothesis has been fairly recent, there is evidence suggesting that declining bioenergy plays a major role in heart failure. This review explored the myocardial ener...

Micronutrients are vitamins and minerals that are essential for human life and health. Deficiencies in these micronutrients are common because of poor quality diets and frequent infectious diseases in low- and middle-income countries. The high prevalence of deficiencies and their important adverse consequences on mortality, morbidity and disability result in a substantial disease burden. In par...

At a cellular level, oxidative stress is known to increase telomere attrition, and hence cellular senescence and risk of disease. It has been proposed that dietary micronutrients play an important role in telomere protection due to their antioxidant properties. We experimentally manipulated dietary micronutrients during early life in zebra finches (Taeniopygia guttata). We found no effects of m...

Helicobacter pylori (HP) infection causes morbidity in several systems, especially in the gastrointestinal tract. The prevalence of disease is inversely related to social-economic and developmental status. It is more common in the developing than in developed countries. In the countries where social-economic status is low, not only HP infection, but also malnutrition and growth failure have a h...

Nutritional supplements are widely used among patients with cancer who perceive them to be anticancer and antitoxicity agents. Depending on the type of malignancy and the gender 30%-90% of the cancer patients supplement their diets with antioxidant and immuno-stabilizing micronutrients, such as selenium, vitamin C, and vitamin D, often without the knowledge of the treating physician. From the o...