BACKGROUND Milder stimulation protocols are being developed to minimize adverse effects of ovarian stimulation in in vitro fertilization (IVF) programs. A drawback is the possibility of an increased rate of insufficient ovarian response. This study aimed to develop a prognostic model for the prediction of cycle cancellation due to insufficient response to mild stimulation. METHODS A total of ...

OBJECTIVE To compare the IVF outcomes of mild ovarian stimulation with conventional ovarian stimulation in poor responders. METHODS From 2004 to 2009, 389 IVF cycles in 285 women showed poor responses (defined as either a basal FSH level ≥12 mIU/mL, or the number of retrieved oocytes ≤3, or serum E(2) level on hCG day <500 pg/mL) were analyzed, retrospectively. In total, 119 cycles with mild ...

background: based on classical two-cell, two-gonadotropin theory, in the follicle, follicle-stimulating hormone (fsh) and luteinizing hormone (lh) put on their main effects on the granulosa and theca cells. lh is essential for androgens production. androgens are used for estradiol production by granulosa cells. profound suppression of lh concentrations in some normogonadotropic patients can cau...

BACKGROUND Failure of IVF treatment after a number of cycles can be devastating for couples. Although mild IVF strategies reduce the psychological burden of treatment, failure may cause feelings of regret that a more aggressive approach, including the transfer of two embryos, was not employed. In this study, the impact of treatment failure after two or more cycles on stress was studied, followi...

abstract background: in order to evaluate the role ofketoconazole in the prevention of ovarian hyperstimulation syndrome (ohss) in women with polycystic ovary syndrome (pcos) undergoing ovarian stimulation with gonadotropins, a prospective, randomized, double-blind, placebo controlled study was done on one-hundred and nine pcos women that had been refeited to be treated by gonadotropins. method...

Royan Institute International Journal of Fertility and Sterility Vol 10, No 2, Jul-Sep 2016, Pages: 264-266 In in vitro fertilization (IVF) programme, the advantages of mild-stimulation have long been appreciated, while there was a called for more patient-friendly approach in ovarian stimulation around 20 years ago (1). However, the concept is yet to get wide-spread acceptance in the IVF commun...

BACKGROUND Given the controversies regarding the effectiveness of gonadotropin-releasing hormone (GnRH) antagonists in prevention of ovarian hyper stimulation syndrome stimulation, this study was designed to compare GnRH agonist protocol with GnRH antagonist protocol in patients who were candidate for assisted reproductive techniques (ARTs). MATERIALS AND METHODS This investigation was perfor...

BACKGROUND To test whether ovarian stimulation for in-vitro fertilization (IVF) affects oocyte quality and thus chromosome segregation behaviour during meiosis and early embryo development, preimplantation genetic screening of embryos was employed in a prospective, randomized controlled trial, comparing two ovarian stimulation regimens. METHODS Infertile patients under 38 years of age were ra...

OBJECTIVE To evaluate the correlation between serum levels of anti-Müllerian hormone (AMH) and ovarian response to mild stimulation in normoovulatory women and anovulatory women with polycystic ovary syndrome (PCOS). METHODS Seventy-four cycles of mild stimulation (clomiphene citrate+gonadotropin followed by timed intercourse or intrauterine insemination) performed in normoovulatory women (57...