Miliary tuberculosis (MTB) of the liver can present non-specifically, which often leads to a diagnostic delay. The objective this clinical case report is highlight an unusual presentation miliary TB in young female patient, who was admitted hospital with right upper quadrant tenderness and constitutional symptoms. Most her investigations yielded little support diagnosis until subsequent positiv...

Annals of Indian Academy of Neurology ¦ Volume 20 ¦ Issue 4 ¦ October-December 2017 431 Sir, The term miliary lesions are defined as innumerable, small lesions (1–4 mm) scattered throughout the lungs or the brain. Tuberculosis is the single most important cause of miliary disease, primary affecting lungs.[1] Many other conditions such as a systemic malignancy, fungal infections, and parasitic i...

Non-HIV immunocompromised patients may develop immune reconstitution inflammatory syndrome (IRIS) as an abnormal response to invading microorganisms, such as Mycobacterium tuberculosis (MTB). IRIS consists in a sudden change in the dominant T-helper responses to inflammation, which is not balanced by anti-inflammatory response, playing a critical role in microbial pathogenesis. A patient with r...

The development of severe adverse reactions to antituberculous drugs in a patient with miliary tuberculosis led to unorthodox, suboptimal antituberculous therapy. The patient's failure to respond to therapy was discovered when acid-fast bacilli were detected in new skin lesions. Such lesions have been described in the literature as tuberculosis cutis miliaris disseminata; 24 cases (in addition ...

BACKGROUND Randomized trials assessing BCG vaccine protection against tuberculosis have widely varying results, for reasons that are not well understood. METHODS We examined associations of trial setting and design with BCG efficacy against pulmonary and miliary or meningeal tuberculosis by conducting a systematic review, meta-analyses, and meta-regression. RESULTS We identified 18 trials r...

Tuberculosis (TB) remains one of the most important causes of death from an infectious disease, and it poses formidable challenges to global health at the public health, scientific, and political level. Miliary TB is a potentially fatal form of TB that results from massive lymphohematogenous dissemination of Mycobacterium tuberculosis bacilli. The epidemiology of miliary TB has been altered by ...

More compatible with 'cryptic miliary tuberculosis' To the Editor—I read with interest the case report published by Shea and Ip titled " Pulmonary tuberculosis complicating asbestosis ". 1 On reading the details, I could not agree on the authors' interpretation of the findings and the diagnosis of asbestosis. While it is beyond doubt that the findings of calcified pleural plaques point towards ...

BACKGROUND BCG vaccine has shown consistently high efficacy against childhood tuberculous meningitis and miliary tuberculosis, but variable efficacy against adult pulmonary tuberculosis and other mycobacterial diseases. We assess and compare the costs and effects of BCG as an intervention against severe childhood tuberculosis in different regions of the world. METHODS We calculated the number...