نتایج جستجو برای: milk hypersensitivities

تعداد نتایج: 71783  

2015
Miau-Hwa Ko Yu-Lin Hsieh Sung-Tsang Hsieh To-Jung Tseng

Wallerian degeneration or nerve demyelination, arising from spinal nerve compression, is thought to bring on chronic neuropathic pain. The widely distributed metabotropic glutamate receptor subtype 5 (mGluR5) is involved in modulating nociceptive transmission. The purpose of this study was to investigate the potential effects of mGluR5 on peripheral hypersensitivities after chronic constriction...

2015
Chao Wang Chunfang Liu Hongye Wan Danhua Wang Danni Sun Tengfei Xu Yue Yang Yakun Qu Ying Xu Xianghong Jing Junling Liu Shuping Chen Zhiqiang Liu Na Lin

Wu-tou decoction (WTD) is a classic traditional Chinese medicine formula and has been used effectively to treat joint diseases clinically. Previous reports indicated that WTD possesses anti-inflammatory activity; however, its actions on pain have not been clarified. Here, we investigated the antinociceptive activity of WTD in CFA-induced mice, and its possible mechanism of the action associated...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2012
Doo-Sik Kim Kang-Wu Li Amin Boroujerdi Yanhui Peter Yu Chun-Yi Zhou Ping Deng John Park Xia Zhang Joshua Lee Michael Corpe Kelli Sharp Oswald Steward Cagla Eroglu Ben Barres Frank Zaucke Zao C Xu Z David Luo

Neuropathic pain is a common cause of pain after nerve injury, but its molecular basis is poorly understood. In a post-gene chip microarray effort to identify new target genes contributing to neuropathic pain development, we report here the characterization of a novel neuropathic pain contributor, thrombospondin-4 (TSP4), using a neuropathic pain model of spinal nerve ligation injury. TSP4 is m...

2014
Jobst Roehmel Carsten Schwarz Anne Mehl Philippe Stock Doris Staab

Background Hypersensitivity reactions to parenteral administered antibiotics (HRPA) are a substantial problem in managing pulmonary disease in Cystic Fibrosis (CF), especially in advanced CF. This group of patients requires a life long antibiotic treatment with extremely high cumulative doses compared to other patients. In our daily routine we observed a growing number of hypersensitivities. Th...

Journal: :Sleep 2023

Abstract Introduction Children with sensory hypersensitivities have poorer subjective sleep health than their peers. However, traditional actigraphy variables (e.g., efficiency, duration) do not adequately capture these deficits. In qualitative interviews, caregivers of children identified the settling down period prior to as a major family stressor, potentially indicating novel target for inte...

2015
D. Kehrli V. Jandova K. Fey P. Jahn V. Gerber

BACKGROUND Multiple hypersensitivities (MHS) have been described in humans, cats, and dogs, but not horses. HYPOTHESES Horses suffering from recurrent airway obstruction (RAO), insect bite hypersensitivity (IBH), or urticaria (URT) will have an increased risk of also being affected by another one of these hypersensitivities. This predisposition for MHS also will be associated with decreased s...

Journal: :Japanese journal of medical science & biology 1975
M Sugimoto A Kojima K Yaginuma Y Egashira

The mouse sensitized by subcutaneous (sc) injection of lysozyme in emulsion of Freund's complete adjuvant (FCA) was shown by a modified footpad test to develop three kinds of hypersensitivities. Injecting lysozyme in 2.5-mul emulsion of Freund's incomplete adjuvant (FIA) into the footpad elicited strong footpad swelling in 30 min (anaphylactic reaction), in 3 hr (Arthus-type reaction) and in 24...

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