Ultra-precision engineering has at its core the size, shape and texture of the components used. This study examines how the relationship between them and their role is changing with respect to manufacture, function and characterization, with particular emphasis on aspects of miniaturization and ultra-precision engineering. Surface geometry has traditionally been linked to the generation of part...

Miniaturisation and automation of bioprocess development continues to be a rapidly expanding area of interest since the technologies promise to reduce biopharmaceutical development time and cost. This meeting will focus on recent technologies used in high throughput bioprocess development, from clone selection through to analysis of final product and formulation. Expert speakers will describe t...

The research in mini, micro and desktop factories originates from the early 90’s and has continued since then by developing the technological basis and different technological building bricks and applications in the field of highprecision manufacturing and assembly of future miniaturised and micro products. This has paved the way for mini, micro and desktop factories which are seen as one poten...

The miniaturization of cation sensitive glass electrodes (Eisenman, 1962) is part of a programme designed to monitor continuously the plasma cationic concentrations in human extracorporeal circulations and in the physiologically normal animal. The investigation of diurnal and metabolic changes in plasma cationic parameters using flame photometry on samples from animals submitted to open operati...

BACKGROUND Molecular diagnostics devices are becoming smaller. With the advancement of miniaturization technologies, microchip-based systems will soon be available for genetic testing. The purpose of this review is to highlight the underlying principles in miniaturization, the strategies being developed for bioanalysis, and the potential impact on the practice of this rapidly growing medical di...

The idea that the damaged brain can functionally reorganize itself - so when one part fails, there lies the possibility for another to substitute - is an exciting discovery of the twentieth century. We now know that motor circuits once presumed to be hardwired are not, and motor-skill learning, exercise, and even mental rehearsal of motor tasks can turn genes on or off to shape brain architectu...

The success of microarrays for analyzing nucleic acid and, more recently, protein-protein interactions illustrates the advantages of bioassay miniaturization. However, the current level of miniaturization of useful bioanalytical tools still creates limits in terms of breadth of application. For example, analyses of picoliter sample volumes containing protein analytes that cannot be amplified or...

this paper presents a miniaturized open-ended rectangular waveguide antenna radiating below the cut-off frequency of the waveguide with a large bandwidth. Waveguide miniaturization is achieved by periodically loading the antenna with electromagnetic metamaterials consisting of infinity shaped resonators. The metamaterial cell is designed to have a high effective dielectric permittivity in the f...