Antibiotic tolerance and persistence are often associated with treatment failure and relapse, yet are poorly characterized. In distinction from resistance, which is measured using the minimum inhibitory concentration metric, tolerance and persistence values are not currently evaluated in the clinical setting, and so are overlooked when a course of treatment is prescribed. In this article, we in...

background and aim: in recent years, due to the indiscriminate and irrational use of synthetic drugs, the resistance of pathogenic microorganisms has increased; therefore, new compounds are vitally needed. the purpose of this study was to investigate the effect of ethanolic and aqueous extracts of berberis vulgaris on escherichia coli, klebsiella pneumoniae, proteus mirabilis, citrobacter frund...

recreational waters should be considered as risks for enterococcal infections in regions with high utilization and long exposure periods. the aim of this study was to investigate the resistance of enterococci to selected antibiotics and some heavy metals [pb+2, fe+2, zn+2 and cr+2]. a total of 75 enterococcal isolates was obtained from 54 bathing and fishing water samples from 9 bathing and fis...

198 lactic acid bacteria (lab) were isolated from iranian milk samples. almost all isolatedlab showed inhibitory activity towards e. coli and s. aureus as gram negative and grampositive indicators, respectively. no role was observed for hydrogen peroxide in the activity ofall isolated strains while organic acids proved a prominent role in all detected inhibitoryactivities. within isolated lab, ...

oral ph sensitive drug delivery systems are of utmost importance as these systems deliver the drug at specific part of the gastrointestine (gi) as per the ph of gi, resulting in improved patient therapeutic efficacy and compliance. the ph range of fluids in various segments of the gi tract may provide environmental stimuli for drug release. the aim of this study was to design buoyant beads cont...

conclusions p. aeruginosa and s. marcescens can be good candidates for the detoxification of cr (vi) in soltan abad river. results the results indicated that pseudomonas aeruginosa and serratia marcescens were the most resistant bacteria with mics of 200 and 150 mg/l, respectively. both bacteria completely reduced 25 and 50 mg/l of cr (vi) in 36 hours and 48 hours, respectively. the growth rate...

background and purpose: essential oils extracted from different plants are extensively used in perfume, beverage, and food industries and are reported to exhibit antimicrobial activities against a variety of fungi. zhumeria majdae belonging to the lamiaceae family is a rare and endemic medicinal plant species in iran, with a strong and pleasant odor. the leaves of this plant have been used for ...

this laboratory study simultaneously was conducted to evaluate the resistance to heavy metals, silver, cadmium and a number of commonly used antibiotics. sampling was done in 2014 of the two silver workshops in isfahan, and the inlet of phase 2 of shahin shahr wastewater treatment plant, isfahan. to isolate resistant bacteria to metal silver and cadmium and review multiple resistance to other m...