نتایج جستجو برای: mir 506

تعداد نتایج: 48412  

ژورنال: ارمغان دانش 2022

Background: Over the past 15 years, significant insights have been gained into the roles of miRNAs in cancer. In various cancers, miRNAs can act as oncogenes, tumor suppressors, or control the metastasis process by modulating the expression of numerous target genes. This study is aimed at determining molecular network of miRNA-mRNA regulating lung cancer invasion, by bioinformatics approaches. ...

2017
Yue Zhang Dong-Hui Guan Rong-Xiu Bi Jin Xie Chuan-Hua Yang Yue-Hua Jiang

BACKGROUND Previous articles have reported that expression levels of microRNAs (miRNAs) are associated with survival time of patients with gastric cancer (GC). A systematic review and meta-analysis was performed to study the outcome of it. DESIGN Meta-analysis. METHODS English studies estimating expression levels of miRNAs with any of survival curves in GC were identified up till March 19, ...

2015
Mitchell S. Stark Vanessa F. Bonazzi Glen M. Boyle Jane M. Palmer Judith Symmons Catherine M. Lanagan Christopher W. Schmidt Adrian C. Herington Robert Ballotti Pamela M. Pollock Nicholas K. Hayward

To identify 'melanoma-specific' microRNAs (miRNAs) we used an unbiased microRNA profiling approach to comprehensively study cutaneous melanoma in relation to other solid malignancies, which revealed 233 differentially expressed (≥ 2 fold, p < 0.05) miRNAs. Among the top 20 most significantly different miRNAs was hsa-miR-514a-3p. miR-514a is a member of a cluster of miRNAs (miR-506-514) involved...

2013
Axel R. Concepcion María Lopez Alberto Ardura-Fabregat Juan F. Medina

The Cl(-)/HCO(-) 3anion exchanger 2 (AE2) is known to be involved in intracellular pH (pHi) regulation and transepithelial acid-base transport. Early studies showed that AE2 gene expression is reduced in liver biopsies and blood mononuclear cells from patients with primary biliary cirrhosis (PBC), a disease characterized by chronic non-suppurative cholangitis associated with antimitochondrial a...

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