Understanding of geographical differences in asthma prevalence may be helpful in explaining recent increases in the occurrence of asthma. We wondered whether differences in allergic sensitization or other factors could explain differences in reported occurrence of asthma between an urban centre and a neighbouring suburban area. From the European Community Respiratory Health Survey (ECRHS) quest...

OBJECTIVES So far, there has been no practical or toxicologically non-hazardous way to decimate mites - without interrupting use of beds - in their main reservoir on bed mattresses to such an extent that the allergic condtion of people suffering from house dust mite allergies is reduced or even remedied. As so-called HygienicWood was effective against mites under simulated conditions, the influ...

Background World Health Organization position paper on immunotherapy recommends using mite allergen vaccines for rhinitis and mild to moderate asthma. Allergic sensitization to domestic mites and particularly to Dermatophagoides pteronyssinus, Dermatophagoides siboney and Blomia tropicalis has been described before in Cuba, as strongly linked to respiratory allergy symptoms. The aim of this wor...

House dust mite (HDM) represents one of the most common sources of aeroallergens worldwide and more than 50% of allergic patients are sensitized to these allergenic molecules. HDM allergy research in the past has been mainly focused on adaptive, mite allergen-dependent immune responses. In recent years it has become clear that, although the allergenspecific CD4+ Th2 cells orchestrate HDM allerg...

Uma vez ocorrida a sensibilização, e a asma se manifestar clinicamente, a exposição persistente aos alérgenos se associa ao aparecimento de sintomas. Portanto, quando a doença já está estabelecida, a exposição ambiental aos alérgenos oferece risco de desencadear crises, dificultando a interpretação da associação entre a asma e a sensibilização alérgica como sendo de causa e efeito. Referências ...

BACKGROUND The purpose of the study was to investigate the influence of environmental allergen exposure on allergic sensitization in infancy and early childhood. METHODS A cohort of 1314 newborns was recruited and followed up prospectively at the ages 12, 24, and 36 months. The levels of major mite (Der p 1 and Der f 1) and cat (Fel d 1) allergens were determined from domestic carpet dust sam...

House dust mites have been shown to be important sources of indoor allergens associated with asthma and other allergic conditions. Asthma is a chronic respiratory disease that affects millions of people worldwide, and numerous scientific studies have shown that the prevalence of asthma is increasing. The most common dust mite species around the world include Dermatophagoides pteronyssinus (Dp),...