this paper aims to investigate the integrated production/distribution and inventory planning for perishable products with fixed life time in the constant condition of storage throughout a two-echelon supply chain by integrating producers and distributors. this problem arises from real environment in which multi-plant with multi-function lines produce multi-perishable products with fixed life ti...

The first 50 years of Integer and Mixed-Integer Programming have taken us to a very stable paradigm for solving problems in a reliable and effective way. We run over these 50 exciting years by showing some crucial milestones and we highlight the building blocks that are making nowadays solvers effective from both a performance and an application viewpoint. Finally, we show that a lot of work mu...

Recently, the area of Mixed Integer Nonlinear Programming (MINLP) has experienced tremendous growth and a flourish of research activity. In this article we will give a brief overview of past developments in the MINLP arena and discuss some of the future work that can foster the development of MINLP in general and, in particular, robust solver technology for the practical solution of problems.