نتایج جستجو برای: mo mtb clo3 system
تعداد نتایج: 2260275 فیلتر نتایج به سال:
Tuberculosis, an infectious disease caused by Mycobacterium tuberculosis (Mtb), remains a major cause of human death worldwide. Innate immunity provides host defense against Mtb. Phagocytosis, characterized by recognition of Mtb by macrophages and dendritic cells (DCs), is the first step of the innate immune defense mechanism. The recognition of Mtb is mediated by pattern recognition receptors ...
Although tuberculous pleurisy (TP) presumably involves a hypersensitivity reaction, there is limited evidence indicating overreactive effector responses of γδ T cells and αβ T cells and their interrelation with Foxp3(+) Tregs in pleural and other compartments. We found that TP induced reciprocal representations of Foxp3(+) Tregs and Mtb phosphoantigen-specific Vγ2Vδ2 T cells in different anatom...
Signals modulating the production of Mycobacterium tuberculosis (Mtb) virulence factors essential for establishing long-term persistent infection are unknown. The WhiB3 redox regulator is known to regulate the production of Mtb virulence factors, however the mechanisms of this modulation are unknown. To advance our understanding of the mechanisms involved in WhiB3 regulation, we performed Mtb i...
The Cobas TaqMan MTB test, based on real-time PCR technology, was evaluated for direct detection of Mycobacterium tuberculosis complex (MTBC) in respiratory specimens. A total of 1,093 samples from 446 patients, including 118 acid-fast smear-positive and 975 acid-fast smear-negative specimens, were investigated. Diagnostic cultures performed with 7H11 agar, Löwenstein-Jensen medium, and the Bac...
The Mouse Tumor Biology Database (MTB) is a Web-based resource that provides access to information on tumor frequency and latency, genetics and pathology in genetically defined mice (transgenics, targeted mutations and inbred strains). MTB is designed to serve as an information resource for cancer genetics researchers who use the laboratory mouse as a model system for understanding human diseas...
Oxidation of Methyl Orange (MO) solution in potassium peroxydisulfate (KPS) homogeneous reaction system without UV irradiation was investigated. The result shows that decolorization of MO increases as the dosage of K2S2O8 increases. The kinetic results demonstrate that the decolorization reaction is a pseudo first-order reaction when the concentration of MO ...
Over the last two decades, a range of minimal invasive surgery (MIS) techniques have been presented to reduce patient recovery time and risks of infection during the surgery. In MIS, incisions are significantly small, as opposed to conventional surgery [1]. The operating range of the needle insertion is limited by the reachability of the needle tip within the human body due to the presence of o...
The rapid detection of antimicrobial resistance is important in the effort to control the increase in resistant Mycobacterium tuberculosis (Mtb). Antimicrobial susceptibility testing (AST) of Mtb has traditionally been performed by the agar method of proportion or by macrobroth testing on an instrument such as the BACTEC (Becton Dickinson, Sparks, MD), VersaTREK (TREK Diagnostics, Cleveland, OH...
Natural chlorate (ClO3?) is widely distributed in terrestrial and extraterrestrial environments. To improve understanding of the origins distribution ClO3?, we developed tested methods to determine multi-dimensional isotopic compositions (?18O, ?17O, ?37Cl, 36Cl/Cl) ClO3? then applied samples natural nitrate-rich caliche-type salt deposits Atacama Desert, Chile, Death Valley, USA. Tests with re...
The ability of the adaptive immune system to restrict Mycobacterium tuberculosis (Mtb) is impeded by activated Foxp3(+) regulatory T (T reg) cells. The importance of pathogen-specific T reg cells in this process has not been addressed. We show that T reg cell expansion after aerosol Mtb infection does not occur until Mtb is transported to the pulmonary lymph node (pLN), and Mtb-specific T reg c...
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