A homologue series of aliphatic streptomycylamines (SM-amines) have been prepared and tested in vitro (binding to 70S ribosomes) and in vivo (MIC). The short-chain SM-amines act as streptomycin (SM) but are less active than SM. They are inactive towards a SM-resistant Escherichia coli, our strain 042. The long-chain SM-amines are active both towards our sensitive and resistant E. coli, our s...

OBJECTIVE A randomized controlled trial was conducted to prospectively compare the therapeutic effectiveness of switching bipolar (SB) radiofrequency ablation (RFA) using cooled-wet electrodes and switching monopolar (SM) RFA using separable clustered (SC) electrodes in patients with hepatocellular carcinomas (HCCs). MATERIALS AND METHODS This prospective study was approved by our Institution...

High-power fiber amplifiers for pulsed applications require large mode area (LMA) fibers having high pump absorption and near diffraction limited output. Photonic crystal fibers allow realization of short LMA fiber amplifiers having high pump absorption through a pump cladding that is decoupled from the outer fiber diameter. However, achieving ultra low NA for single mode (SM) guidance is chall...

Multi-core fibers (MCFs) with coupled-cores are attractive large-mode area (LMA) specialty fiber designs that support the propagation of a few transverse modes often called supermodes (SMs). Compared to other LMA fibers, the uniqueness of MCF arises from the higher degrees of design space offered by a multitude of core-array geometries, resulting in extended flexibility to tailor SM properties....

This paper develops a fractional-order sliding mode based extremum seeking controller (FO SM-ESC) for the optimization of nonlinear systems. The proposed FO SM-ESC, involving an FO derivative function 0D q t sgn(e), 0 ≤ q < 1 is shown to achieve faster tracking and higher control accuracy than the integerorder (IO) SM-ESC. The tradeoff between control performance and parameters selection is ana...

We propose Hybrid Transactional Replication (HTR) a novel replication scheme for highly dependable services. It combines two schemes: a transaction is executed either optimistically by only one service replica in the deferred update mode (DU), or deterministically by all replicas in the state machine mode (SM); the choice is made by an oracle. The DU mode allows for parallelism and thus takes a...

Pore-forming proteins insert from solution into membranes to create lesions, undergoing a structural rearrangement often accompanied by oligomerization. Lysenin, a pore-forming toxin from the earthworm Eisenia fetida, specifically interacts with sphingomyelin (SM) and may confer innate immunity against parasites by attacking their membranes to form pores. SM has important roles in cell membrane...

In this paper we study the properties of protocol independent multicast (PIM) in non-strictly hierarchical network environments. In particular, we investigate the cost (overhead) behaviour of the PIM protocols i.e., sparse mode (PIM-SM), dense mode with flood and prune mechanism (PIM-DMFP), dense mode with state refresh (PIM-DMSR), and source specific multicast (PIM-SSM). By assuming that the l...

this paper proposes a hybrid control scheme for the synchronization of two chaotic duffing oscillator system, subject to uncertainties and external disturbances. the novelty of this scheme is that the linear quadratic regulation (lqr) control, sliding mode (sm) control and gaussian radial basis function neural network (grbfnn) control are combined to chaos synchronization with respect to extern...

We study the observability for a Higgs boson at upgraded Tevatron via the modes gg → h → ZZ → 4l (l = e, μ). We find that the signal can be observed at an integrated luminosity of 30 fb if the fourth SM family exists. In the Standard Model (SM) one doublet of scalar fields is assumed, leading to the existence of one neutral scalar particle h. The requirements of the stability of the electroweak...