Eleven years ago, on June 1, 1991, Dr J.P. Mohr addressed delegates of the International Conference on Stroke, Geneva, about anticoagulants as a therapeutic strategy in stroke. He bemoaned the fact that heparin and warfarin had the “bad luck” to be manufactured initially in the post–World War II period, before drugs were evaluated by controlled clinical trials. As a consequence, clinicians judg...

A new method for implicit integration of the Mohr-Coulomb non-smooth multisurface plasticity models is presented, and Koiter’s requirements are incorporated exactly within proposed algorithm. Algorithmic numerical complexities identified introduced by nonsmooth intersections surfaces; then, a projection contraction algorithm applied to solve classical Kuhn–Tucker complementary equations which p...

The oral-facial-digital syndromes (OFD) are part of a great number of genetic disorders. They are classified in categories based on characteristic abnormalities, including OFD type I (Papillon-Leage and Psaume syndrome) and OFD type II (Mohr syndrome). The aim of this article is to describe a clinical case of a patient with oralfacial-digital type II syndrome or Mohr syndrome, who underwent sur...

We describe a constellation of distinctive skeletal abnormalities in an 8-year-old boy who presented with the full clinical criteria of oro-facial-digital (OFD) type II (Mohr syndrome): bony changes of obtuse mandibular angle, bimanual hexadactyly and unilateral synostosis of the metacarpo-phalanges of 3-4, bilateral coxa valga associated with moderate hip subluxation, over-tubulation of the lo...

This special issue offers papers that together reach toward sociological understanding of “meaning.” We contextualize that effort in intersecting intellectual trends—the emerging relational sociology of networks and meanings, which has progressed steadily since the 1990s, and the diverse enterprise of sociology of language, which is much less established in the U.S. Given space limitations, we ...

Eleven years ago, on June 1, 1991, Dr J.P. Mohr addressed delegates of the International Conference on Stroke, Geneva, about anticoagulants as a therapeutic strategy in stroke. He bemoaned the fact that heparin and warfarin had the “bad luck” to be manufactured initially in the post–World War II period, before drugs were evaluated by controlled clinical trials. As a consequence, clinicians judg...

Abstract Extension fractures are typical for the deformation under low or no confining pressure. They can be explained by a phenomenological extension strain failure criterion. In past, simple empirical criterion fracture initiation in brittle rock has been developed. this article, it is shown that makes unrealistic strength predictions biaxial compression and tension. To overcome major limitat...