Centella asiatica extract is a rich source of natural bioactive substances, triterpenoid saponins, flavonoids, phenolic acids, triterpenic steroids, amino acids and sugars. Thus, many scavenging free radicals, exhibit antiinflammatory activity and affect on the stratum corneum hydration and epidermal barrier function. The aim of the present study was to evaluate the in vivo moisturizing and ant...

The objectives of the present study were isolation, identification and characterization of xylanase producing fungi, optimization of medium composition and cultural conditions for xylanase enzyme production using cheaper sources. The fungal strains were isolated from garden soil by serial dilution technique and Aspergillus niger was identified and isolated in pure form. In conformation screenin...

Genes of the S100 fused-type protein (SFTP) family are clustered within the epidermal differentiation complex and encode essential components that maintain epithelial homeostasis and barrier functions. Recent genetic studies have shown that mutations within the gene encoding the SFTP filaggrin cause ichthyosis vulgaris and are major predisposing factors for atopic dermatitis. As a vital compone...

Atopic dermatitis, the most common form of eczema, is a chronic, relapsing inflammatory skin condition that occurs with dry skin, persistent itching, and scaly lesions. This debilitating significantly compromises patient’s quality life due to intractable itching other associated factors such as disfigurement, sleeping disturbances, social stigmatization from visible The treatment mainstay atopi...

Bu çalışma kapsamında, pandemi ile hayatımıza giren maskelerin cilde verdiği rahatsızlığı azaltmak amacıyla kozmetik sektöründe de nemlendirici özelliği yaygın olarak kullanılan moringa yağının %100 pamuklu ve yıkanabilir maskelere lipozomlar aktarılması amaçlanmıştır. amaçla yağı içeren 3 farklı konsantrasyonda lipozom üretilmiş, SEM partikül boyut analizi optimizasyon çalışmaları gerçekleştir...

BACKGROUND The stingless bee is a natural type of bee that exists in almost every continent. The honey produced by this bee has been widely used across time and space. The distinctive feature of this honey is that it is stored naturally in the pot (cerumen), thus contributing to its beneficial properties, especially in the wound healing process. METHODS In this article, several studies on sti...

Corticosteroids are currently the first line of treatment for patients with atopic dermatitis. In the pediatric population however, the potential impact of adrenal suppression is always an important safety concern. Twenty boys and girls, 5-12 years of age, with normal adrenal function and a history of atopic dermatitis were maximally treated three times daily with a lipid-rich, moisturizing for...