نتایج جستجو برای: molecular histopathology
تعداد نتایج: 659372 فیلتر نتایج به سال:
Worldwide use of formalin-fixed paraffin-embedded blocks (FFPE) is extensive in diagnosis and research. Yet, there is a lack of optimized/standardized protocols to process the blocks and verify the quality and presence of the targeted tissue. In the context of an international study on head and neck cancer (HNC)-HPV-AHEAD, a standardized protocol for optimizing the use of FFPEs in molecular epi...
Molecular pathology has become an essential adjunct in the realm of diagnostic histopathology. While gains in this field have been enjoyed in many areas, their impact has arguably been greatest felt in bone and soft tissue pathology. The purpose of this paper is to highlight the emerging role of molecular techniques in the context of paediatric bone pathology, discussing select syndromic and ne...
Introduction Colorectal cancers are the third most common type of cancers globally, affecting both sexes [1]. As of now, histopathology is the gold standard method for colon cancer diagnosis. Newer technologies are the important need of the hour to complement the existing approaches, for better understanding the onset and progression of the disease. Infrared (IR) imaging could be a potential ca...
Histopathology, the examination of an architecturally artefactual, two-dimensional and static image remains a potent tool allowing diagnosis and empirical expectation of prognosis. Considerable optimism exists that the advent of molecular genetic testing and other biomarker strategies will improve or even replace this ancient technology. A number of biomarkers already add considerable value for...
Introduction: The study was conducted to understand the clinical algorithm of hepatocellular carcinoma (HCC). Correlation was done by clinical presentation with radiological features and histopathology of HCC. The stress on to understand the necessity for a team approach between clinician, radiologist, and pathologist and vice versa is emphasized. Aim: To correlate histopathology of HCC with th...
Introduction: This study was conducted to understand the clinical algorithm of renal cell carcinoma (RCC). Correlation was done by a clinical presentation with radiological features and histopathology of RCC. The stress upon to understand the necessity for a team approach between clinician, radiologist, and pathologist and vice versa is emphasised. Aim: The aim of this study was to correlate th...
Contributions of Histopathology and Molecular Biology for the Discovery of Genodermatoses in Animals
Research in pathology has increasingly come to involve molecular techniques, so that these are currently routine in academic histopathology and genetics laboratories. Molecular markers—largely from tumours, but also from the germline—have great potential for diagnosis, for directing treatment, and as indicators of outcome. However, in general, clinical practice has lagged behind research in mol...
Identification of the tissue of origin in cancer of unknown primary (CUP) poses a diagnostic challenge and is critical for directing site-specific therapy. Currently, clinical decision-making in patients with CUP primarily relies on histopathology and clinical features. Comprehensive molecular profiling has the potential to contribute to diagnostic categorization and, most importantly, guide CU...
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