نتایج جستجو برای: monobactams
تعداد نتایج: 1571 فیلتر نتایج به سال:
BACKGROUND There have been few studies regarding the cross-reactivity and tolerability of penicillins, aztreonam, and carbapenems in large samples of subjects with cephalosporin allergy. OBJECTIVE We sought to evaluate the possibility of using penicillins, monobactams, and carbapenems in subjects with cephalosporin allergy who especially require them. METHODS We conducted a prospective stud...
SHV-5, a novel SHV-type beta-lactamase that hydrolyzes broad-spectrum cephalosporins and monobactams
22 Resistance to ß-lactams is constantly increasing, due to the emergence of totally new 23 enzymes, but also to the evolution of pre-existing ß-lactamases. GES-1 is a clinically24 relevant extended-spectrum -lactamase (ESBL) hydrolyzing penicillins and broad25 spectrum cephalosporins, but sparing monobactams and carbapenems. However, 26 several GES-1 variants (i.e. GES-2 and GES-5) previously ...
Macrolide antibiotics are thought to clog up the ribosomal tunnel and thereby block general protein synthesis. By using a combination of elegant in vivo and in vitro approaches, Kannan et al. show that the inhibitory action of these drugs on bacterial protein synthesis is selective rather than global.
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