نتایج جستجو برای: monoclonal anti d
تعداد نتایج: 961388 فیلتر نتایج به سال:
Background: ABO and Rh blood group antigens are inherited traits ,located on chromosome 1 and19. They usually not altered throughout the life of an individual. Blood grouping consists forward reverse both procedures should match with each other. A discrepancy exists when results do be resolved before transfusion to properly labeled prevent reaction. Methods: prospective study was carried out in...
background: human cd34 is a transmembrane glycoprotein which is expressed in human hematopoietic stem cells (hscs) and the small- vessel endothelial cells of a variety of tissues. cd34 plays a critical role as a marker for diagnosis and classification of leukemia. anti cd34 antibodies are used for isolation and purification of hscs from bone marrow, peripheral blood and cord blood. objective: t...
Multiple sclerosis is a common leading cause of disability worldwide. CD20-expressing B cells play major role in multiple pathogenesis. Hence, anti-CD20 monoclonal antibodies effectively deplete mainly by complement-dependent cytotoxicity, antibody-dependent cell-mediated phagocytosis, and cellular cytotoxicity. While the precise etiology remains unknown, it now recognized that environment...
The Thomsen-Friedenreich antigen (T-antigen) is a cryptic disaccharide structure on human erythrocytes and is supposed to be expressed in an unhidden form on carcinoma cells. We tested the ability of four antiT reagents (i.e., peanut agglutinili, human and rabbit anti-T antisera, and monoclonal anti-T antibodies) to agglutinate neuraminidase treated hu man erythrocytes and compared their capaci...
RhD antigen is the most immunogenic and clinically significant antigen of red blood cells after ABO system. It has historically been associated with hemolytic disease of the newborn (HDN) which is now routinely prevented by the administration of polyclonal anti-D immunoglobulin. This management of HDN has proven to be one of the most successful cases of prophylactic treatment based on antibody ...
CD39 is an extracellular ectonucleotidase highly expressed in the tumor microenvironment (TME) that, sequentially with CD73, contributes to production of adenosine (Ado), via hydrolysis triphosphate (ATP). IPH5201 a blocking anti-CD39 monoclonal antibody (mAb) that may promote antitumor immunity by accumulating immunostimulatory ATP released necrotic cells and reducing immunosuppressive Ado lev...
Colorectal cancer is considered a disease of the elderly population. Since the number of geriatric patients continues to rise, monoclonal antibody therapy is the most promising therapy in the recent research. Presently, the monoclonal antibodies most frequently used in the treatment of colorectal tumors are bevacizumab, cetuximab, panitumumab, and ramucirumab. Bevacizumab is a monoclonal antibo...
We evaluated the efficacy of a neutralizing anti-high mobility group box 1 (HMGB1) monoclonal antibody in MRL/lpr lupus-prone mice. The anti-HMGB1 monoclonal antibody (5 mg/kg weight) or class-matched control immunoglobulin G2a (IgG2a) was administered intravenously twice a week for 4-15 weeks. Urine albumin was monitored, and histological evaluation of the kidneys was conducted at 16 weeks. Ly...
در حال حاضر ivig و anti d از درمان های معمول itp می باشند.دربرخی مطالعات تأثیراین دو دارو با هم یکسان بوده و در برخی مطالعات تأثیرات متفاوتی از این دارو در افزایش پلاکت بیماران مبتلا به itp گزارش شده است.
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