Implication for health policy makers/practice/research/medical education: This article aims to introduce saffron as a useful herbal medicine. Copyright © 2014, School of Pharmacy, Ahvaz Jundishapur University of Medical Sciences; Published by DOCS. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution...

In a n c,," method fo r prepar ing aldoses labeled wit h Lritium at ca r bon l , Lhc aldoni c lactone l S rcdu ced with li thium boro.hyddde-I in p yridine soluLion . The mcthod is suitablc for prcparing aldosesl -1 h a vin g high specifi c act ivit ies. Thc crudc product con tains a substant ia l proport ion of t hc c<?lTespondin g a ldi tol-l-I, but t he purc aldosc-l-1 is rcadil y scparated ...

4-(imidazoyl-1-yl)butanamide derivatives as antimuscarinic activity agents were reported by the Kyorin Discovery Research group. Among them, 4-(2-methyl-1H-imidazol1-yl)-2,2-diphenylbutanamide [KRP-197/ONO-8025, 1] is under clinical evaluation as a new type of treatment for urinary incontinence with highly subtype receptor selective antimuscarinic activity. During the course of the metabolite s...

Die fermentative Ganzzellproduktion in Escherichia coli ermöglicht die Produktion komplexer Naturstoffe, wie Terpene, aus einfachen, günstigen und nachhaltigen C-Quellen. Ziel der Arbeit war es, einen solchen Prozess zur Synthese von Presilphiperfolan-8β-ol (PSP) zu entwickeln. Der Biosyntheseweg dieses tricyclischen Sesquiterpenalkohols konnte erfolgreich E. eingebracht werden. resultierende M...