The iron storage macrophage has been Isolated from the marrow of Imforontreated mice and studied in vitro by morphologic, histochemical, and functional tests and isotope labeling techniques. Those macrophages on stained preparations are large, many times binucleate cells (up to 150 ii), and show Prussian blue reactivity. In Epon-embeddod, stained thick sections they contain elongated narrow bas...

OBJECTIVES To describe the morphologic characteristics of skin lesions, extent of extracutaneous disease, and outcomes in patients with neonatal presentation of Langerhans cell histiocytosis (LCH), and to examine clinical predictors of disease prognosis. DESIGN Retrospective validation cohort study. Maximum duration of follow-up was 10 years. SETTING A tertiary care children's hospital in C...

PURPOSE No clinically useful target molecule has been identified for triple-negative (TN) breast cancer, i.e., estrogen receptor-negative, progesterone receptor-negative, human epidermal growth factor receptor-2-negative phenotype, and its prognosis is poor. The aim of this study is to clarify the clinical and pathologic characteristics of triple negative breast cancer (TNBC). METHODS The stu...

BACKGROUND AND PURPOSE Gray matter heterotopia have been divided into three groups based on clinical and imaging characteristics: subependymal, subcortical, and band heterotopia. Nonetheless, subcortical heterotopia can have variable morphologic findings. The purpose of this study was to perform a morphologic analysis of a series of cases of subcortical heterotopia based on MR images, to correl...

To examine the possible relationship between systemic HT and SAS we compared 21 hypertensive (HT+) and 29 normotensive (HT-) patients for morphologic characteristics, sleep disturbances and respiratory events monitored during a full night polysomnography. There was no significant difference between HT+ and HT- patients with respect to age, weight, BMI, sleep stage distribution and disorganizati...