The objective was to describe and recommend the most effective combination of Natural-Based Product (NBP) mucoadhesive for Recurrent Aphthous Stomatitis (RAS) treatment. This systematic review writing based on PRISMA guidelines. articles published in last 10 y were selected using PubMed Google Scholar database carried out during May 2021. keywords were: natural-based product, mucoadhesive, Stom...

Magnetically-actuated soft robots for medical applications are required to be functional, biocompatible, as well capable of robust motion inside human organs. In this paper, a ring-shaped magnetic robot, with flexible biopolymeric film coating, on mucus-coated surfaces is designed and investigated. The made from chitosan–glycerol (C–G) solution endows the robot locomotion capabilities diverse g...

Mucoadhesive durg delivery systems are among novel drug delivery systems that due to their ability to adhere and remain on the mucosal surfaces and a show and sustained release of their drug contect have attracted special attention in recent years.the aim of this study was to evaluate the effect of four different important factors on the  mucoadhesive strength of a few  mucoadhesive polymers.am...

Objective: Buccal drug delivery is the most suited route for local as well systemic of drugs. Cilnidipine an L/N type dihydropyridine 4th generation calcium channel blocker (CCB), which decreases hypertension by blocking N-type to attenuate vascular sympathetic neurotransmission. It has high first-pass metabolism leading low bioavailability. Hence present research work was undertaken formulate ...

Micro- and nanofabrication techniques have revolutionized the pharmaceutical and medical fields as they offer the possibility for highly reproducible mass-fabrication of systems with complex geometries and functionalities, including novel drug delivery systems and bionsensors. The principal micro- and nanofabrication techniques are described, including photolithography, soft lithography, film d...

The purpose of the study is to formulate and evaluate a new, cheap and effective natural mucoadhesive agent that can be used as an effective alternative for traditional mucoadhesive agent. The study procedure involved extraction of mucoadhesive agent from the Trigonellafoenumgraecum (fenugreek) seeds, solubility testing of the mucilage obtained, phytochemical testing, determination of swelling ...

The aim of this study was to formulate buccal mucoadhesive nanoparticles (NPs) using the natural mucoadhesive polymers. The natural mucoadhesive polymers chitosan (CS) and dextran sulfate sodium salt (DS) were used to prepare mucoadhesive NPs using the ionic gelation method. As the molecular weight of DS decreased, the amount of mucin and the number of buccal cells adsorbed on DS increased. The...

In present study, mucoadhesive vaginal tablet of sertaconazole was designed using a combination of mucoadhesive polymers like Carbopol 934P, chitosan, carboxymethylcellulose sodium, sodium alginate, methyl cellulose, hydroxypropyl methylcellulose and hydroxypropyl cellulose. Effervescent was incorporated into formulations to enhance swellabilty of mucoadhesive tablet. For various drug-free form...

Department of Pharmaceutical Technology, Meerut Institute of Engineering & Technology, NH-58, Baghpat Road-Bypass Crossing, Meerut-250005 (U.P), India ABSTRACT Drug release from mucoadhesive patches at predetermined rate in oral cavity having distinct advantages over traditional dosage forms as tablets, gels and solutions. This review provides brief information about method of preparation and e...