In the title mol-ecule, C(15)H(17)NO(3)S, the C-S-N-C(benzene) torsion angle is 81.45 (16)°, and the two aromatic rings form a dihedral angle of 45.83 (12)°. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into chains parallel to the b axis.

Four 4-phthalimide derivatives of N-(3-chlorophenyl)-2-picolinamide were synthesized as potential ligands for the PET imaging of mGlu4 in the brain. Of these compounds, N-(3-chloro-4-(4-fluoro-1,3-dioxoisoindolin-2-yl)phenyl)-2-picolinamide (3, KALB001) exhibited improved binding affinity (IC50 = 5.1 nM) compared with ML128 (1) and was subsequently labeled with (18)F. When finally formulated in...

[Cp*IrLnCl] complexes [L1 = (methyl-β-d-glucopyranosid-2-yl)picolinamide, 1; L2 (methyl-3,4,6-tri-O-acetyl-β-d-glucopyranosid-2-yl)picolinamide, 2; L3 (2,3,4,6-tetra-O-acetyl-β-d-glucopyranosid-1-yl)picolinamide, 3] have been synthesized and completely characterized in solution, by 1D- 2D-NMR spectroscopy, the solid state, X-ray single crystal diffractometry. Despite chirality of Ln-moiety meta...

In the title compound, C(18)H(21)N(3)O(2)S·0.5H(2)O, the benzene ring makes dihedral angles of 88.59 (6) and 40.74 (8)° with the pyridine ring and the amide group, respectively. The water O atom lies on a twofold axis. In the crystal, the organic mol-ecules and the water mol-ecules are linked via O-H⋯O hydrogen bonds, while the organic mol-ecules are connected to each other via N-H⋯O hydrogen b...

In the mol-ecule of the title compound, C(17)H(17)NO(5)S, the two aromatic rings are oriented at an angle of 30.13 (10)°. The ethyl acetate group assumes an extended conformation. Mol-ecules are linked into C(7) chains running along the a axis by inter-molecular C-H⋯O hydrogen bonds, and the chains are crosslinked via C-H⋯π inter-actions, with the sulfonyl-bound phenyl ring acting as an acceptor.