نتایج جستجو برای: n arylidene 2 2 phenoxyphenyl acetohydrazide derivatives
تعداد نتایج: 3204168 فیلتر نتایج به سال:
The first iron(III)/N,N'-dioxide-catalyzed asymmetric haloamination of 3-alkylidene- and 3-arylidene-indolin-2-ones was developed, affording the corresponding chiral oxindole derivatives bearing vicinal haloamine substituents with excellent results (up to 99% yield, 99% ee, >19 : 1 dr). This iron catalyst also exhibits perfect enantioselectivity for chalcone derivatives. The cooperative activat...
Herein, we describe the synthesis and pharmacological evaluation of novel N-phenylpyrazolyl-N-glycinyl-hydrazone derivatives that were designed as novel prototypes of p38 mitogen-activated protein kinase (MAPK) inhibitors. All of the novel synthesized compounds described in this study were evaluated for their in vitro capacity to inhibit tumor necrosis factor α (TNF-α production in cultured mac...
A new reaction of 4-arylidene-3-methylisoxazol-5(4H)-one or 4-arylidene-2-phenyloxazol-5(4H)-one with 2,6-diaminopyrimidin-4(3H)-one is described and a number of new pyrido[2,3-d]pyrimidine-4,7-dione derivatives are synthesized. This protocol has the advantages of good yields, broad substrate scope and simple work-up.
The syntheses of two benzylidenehydrazine derivatives, namely, ( E )- N ′-(4-chloro-3-nitrobenzylidene)acetohydrazide, C 9 H 8 ClN 3 O , and )-2-(4-chlorobenzylidene)-1-(quinolin-8-yl)hydrazine, 16 12 are reported. molecules have been characterized using IR, 1 NMR, 13 NMR mass spectroscopic elemental analysis techniques, their structures determined by single-crystal X-ray diffraction.
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