completely novel structure in this class of compounds. Fermentation and Isolation Cremeomycinwas originally reported by Bergy and Pyke at the Upjohn Company in 1967 from Streptomyces cremeus NRRL3241.11} Neither a structural formula nor functional group information was reported. Physico-chemical and Biological Properties Cremeomycinis a bright yellow solid that is soluble in solvents from dichl...

The purpose of this study was to characterize the kinetics and voltage-dependence of the block of N-methyl-D-aspartate (NMDA)-induced currents in primary cultures of rat cortical neurons by the neuroprotective, low-affinity, NMDA antagonist ARL 15896AR, using whole-cell voltage-clamp techniques. ARL 15896AR caused rapid and reversible inhibition of NMDA (50 microM)-evoked currents from neurons ...

Mycophenolic acid is a secondary extracellular metabolite of Penicillium strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive uses. The aim of this work is the survey of the effect of phenylglyoxal and n-ethylmaleimide concentration in culture medium on mycophenolic acid production by Penicillium brevi-compactum ATCC16024 was investigated. Batch submerged fer...

Mycophenolic acid is a secondary extracellular metabolite of Penicillium strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive uses. The aim of this work is the survey of the effect of phenylglyoxal and n-ethylmaleimide concentration in culture medium on mycophenolic acid production by Penicillium brevi-compactum ATCC16024 was investigated. Batch submerged fer...

the aim of this study was to investigate the genotype effect on nitrogen remobilization and its relationship with yield and grain protein concentration in genotypes of wheat during grain filling. twelve wheat cultivars different in origin and varying with grain yield and grain protein percentage were selected. a randomized complete block design was used. plants were harvested at anthesis and ma...

in order to evaluate different sources and rates of nitrogen on dry matter yield, concentration and uptake of primary macronutrients (nitrogen, phosphorous and potassium) in forage sorghum (hybrid of speedfeed), three levels of nitrogen (80, 160 and 240 kg n ha-1) from three n sources (urea fertilizer, cattle manure and equal combination of urea fertilizer + cattle manure) and the control (no f...