The potency of Pb2+ inhibition of glutamate-activated currents mediated by N-methyl-D-aspartate (NMDA) receptors was dependent on the subunits composing the receptors when functionally expressed in Xenopus laevis oocytes. Pb2+ reduced the amplitudes of glutamate-activated currents and shifted the agonist EC50 values of NMDA receptors consisting of different subunit compositions. The IC50 values...

We report electrochemical studies and the observation of excimer emission from the conjugated polymer poly(9,9-dioctylfluorene) (PDOF) in benzene-MeCN solutions during electrogenerated chemiluminescence (ECL). The ECL emission spectrum resulting from the annihilation reaction between PDOF radical ions is characterized by two bands, one at 438 nm and a broad band centered at 610 nm. The ECL emis...

Imatinib is a selective breakpoint cluster region-Abelson (BCR-ABL) tyrosine kinase inhibitor (TKI) that has significantly improved the prognosis of patients with chronic myeloid leukemia (CML). However, T315I gene mutations of the BCR-ABL kinase domain have been shown to confer resistance to imatinib. In the present study, we synthesized a novel BCR-ABL inhibitor, HS-438, and identified its an...

OBJECTIVE To evaluate diagnostic value of vaginal pH and cervical length measurement in the second trimester of pregnancy as a preterm labor (PTL) predictor. METHODS During a prospective cohort study 438 uncomplicated singleton pregnant women between 18 and 24 weeks of gestation were assessed regarding vaginal PH and cervical length. Vaginal pH was measured using Ph-indicator strips and cervi...

European Review / Volume 23 / Issue 03 / July 2015, pp 426 438 DOI: 10.1017/S1062798715000113, Published online: 02 June 2015 Link to this article: http://journals.cambridge.org/abstract_S1062798715000113 How to cite this article: Sowon S. Park (2015). An Unknown Masterpiece: On Pak Kyongni’s Land and World Literature. European Review, 23, pp 426-438 doi:10.1017/S1062798715000113 Request Permis...

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BACKGROUND Recent research has shown a correlation between immune microenvironment and lymphoma biology. This study aims to investigate the prognostic significance of the immunologically relevant lymphocyte-to-monocyte ratio (LMR), in diffuse large B-cell lymphoma (DLBCL) in the rituximab era. METHODOLOGY/PRINCIPAL FINDINGS We analyzed retrospective data from 438 newly diagnosed DLBCL patient...

Nitrification is a necessary and often limiting process in animal waste treatment for removal of nitrogen as N2 through biological nitrification/denitrification systems. We evaluated three technologies for enhancing nitrification of pig lagoon wastewater prior to denitrification: overland flow, trickling filter, and a bioreactor using nitrifying pellets. The overland flow system consisted of a ...