Background & aim: Knowledge and attitude of the nurses and midwives towards HIV/AIDS patients could affect the quality of care provision. Thus, this study aimed to determine the relationship between knowledge, attitude, and tendency of nurses and midwives towards caring for HIV/AIDS patients. Methods: This cross-sectional study was conducted on 303 nurses and midwives at healthcare centers, af...

BACKGROUND In January 2014, the European Medicines Agency issued a marketing authorization for dolutegravir (DTG), a second-generation integrase strand transfer inhibitor for HIV treatment. The study aimed at determining the incremental cost-effectiveness ratio (ICER) of the use of DTG+backbone compared with raltegravir (RAL)+backbone, darunavir (DRV)+ritonavir(r)+backbone and efavirenz/tenofov...

The interaction between genetic predisposition and environmental factors are of great significance in the pathogenesis and development of autoimmune diseases (AIDs). The human mucosa is the most frequent site that interacts with the exterior environment, and commensal microbiota at the gut and other human mucosal cavities play a crucial role in the regulation of immune system. Growing evidence ...

background and aims: genotyping assay has been accepted as a guidance in the therapeutic management of human immunodeficiency virus 1 (hiv-1). but, it is not commonly used in our country due to its high running cost. the aim of this study is evaluate an in-house genotyping resistance test (grt) for hiv-1. methods: hiv-1 rna of 20 samples were extracted from plasma and rt nested- pcr was perform...

OBJECTIVE To determine the response on treatment-naïve HIV/AIDS patients to the Highly Active Antiretroviral Therapy (HAART) in terms of CD4 Count and Weight gain over a period of 2 1/2 years. METHODS Patients with Acquired Immunodeficiency Syndrome (AIDS) were recruited under the Federal Government Highly Active Antiretroviral Therapy (HAART) programme at the University of Ilorin Teaching Ho...

Background. Sensory neuropathy (SN) is one of the most common AIDS-associated neurologic disorders especially in the era of highly active antiretroviral therapy (HAART). The aim of this study was to determine the prevalence of SN among highly-active-antiretroviral-therapy- (HAART-) experienced and HAART-naïve HIV-positive individuals and to investigate the relationship to demographic, clinical,...

background & objective: interleukin (il)-10 is an important anti-inflammatory and immunomodulatory cytokine. some authors believe that single nucleotide polymorphisms (snp) in the promoter region of the il-10 gene have been associated with susceptibility to hiv infection and progression to aids, but its role is not clearly defined yet. the present study was undertaken to evaluate the associ...

AIM We studied the prevalence of resistance mutations in drug-naïve HIV-infected individuals at the Bela-Bela treatment site to gather information on the presence of antiretroviral (ARV) drug-resistant viruses in drug-naïve populations, so as to improve treatment guidance. SUBJECTS AND METHODS Drug-naïve HIV-l1-infected individuals were sequentially recruited between February 2008 and Decembe...

background & aim: knowledge and attitude of the nurses and midwives towards hiv/aids patients could affect the quality of care provision. thus, this study aimed to determine the relationship between knowledge, attitude, and tendency of nurses and midwives towards caring for hiv/aids patients. methods: this cross-sectional study was conducted on 303 nurses and midwives at healthcare centers, aff...

Background & Objective: Interleukin (IL)-10 is an important anti-inflammatory and immunomodulatory cytokine. Some authors believe that single nucleotide polymorphisms (SNP) in the promoter region of the IL-10 gene have been associated with susceptibility to HIV infection and progression to AIDS, but its role is not clearly defined yet. The present study was undertaken to evaluate the a...